ID   F7NGU4_9FIRM            Unreviewed;       870 AA.
AC   F7NGU4;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:EGO64675.1};
GN   ORFNames=ALO_06428 {ECO:0000313|EMBL:EGO64675.1};
OS   Acetonema longum DSM 6540.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC   Acetonema.
OX   NCBI_TaxID=1009370 {ECO:0000313|EMBL:EGO64675.1, ECO:0000313|Proteomes:UP000003240};
RN   [1] {ECO:0000313|EMBL:EGO64675.1, ECO:0000313|Proteomes:UP000003240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6540 {ECO:0000313|EMBL:EGO64675.1,
RC   ECO:0000313|Proteomes:UP000003240};
RX   PubMed=21673657; DOI=10.1038/emboj.2011.186;
RA   Chen S., Beeby M., Murphy G.E., Leadbetter J.R., Hendrixson D.R.,
RA   Briegel A., Li Z., Shi J., Tocheva E.I., Muller A., Dobro M.J.,
RA   Jensen G.J.;
RT   "Structural diversity of bacterial flagellar motors.";
RL   EMBO J. 30:2972-2981(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGO64675.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AFGF01000050; EGO64675.1; -; Genomic_DNA.
DR   RefSeq; WP_004093955.1; NZ_AFGF01000050.1.
DR   AlphaFoldDB; F7NGU4; -.
DR   STRING; 1009370.ALO_06428; -.
DR   eggNOG; COG0639; Bacteria.
DR   eggNOG; COG4639; Bacteria.
DR   OrthoDB; 9779903at2; -.
DR   Proteomes; UP000003240; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd07423; MPP_Prp_like; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR041780; MPP_PrpE-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR024028; PNKP_bac.
DR   InterPro; IPR032380; PNKP_ligase_dom.
DR   InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR   NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR   PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR   PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16542; PNKP_ligase; 1.
DR   PRINTS; PR00114; STPHPHTASE.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003240}.
FT   DOMAIN          181..378
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          474..865
FT                   /note="Polynucleotide kinase-phosphatase ligase"
FT                   /evidence="ECO:0000259|Pfam:PF16542"
SQ   SEQUENCE   870 AA;  97293 MW;  F9B18C254E79D4BC CRC64;
     MELMLPELSL VLLIGPSGCG KSTFARRHFK PTEVISSDFC RGLVADDEND QAVNNPAFEV
     LHYIAGKRLQ LGKLTVVDAT NVQEAARKPL LQLARDHHCI PVAIVLNLPE RVCQDRNKSR
     TDRQVGDYVI KNHIAQLRRS LRNLRKEGFR QVYVLNSPEE VEQVQCRRQP LWNNLKHEHG
     PFDIIGDVHG CFAELKMLLA NMGYMVEETV DAAGEKDFRA AHPDGRKAIF LGDLVDRGPR
     TADTLKLVMA MVRDGNALCV PGNHDVKLLK KLKGGNVQVT HGLGETLAQL ESESPAFIAK
     VKLFIDGLIS HYVLDDGKLV VAHAGMKENL QGRGSGKVRD FALYGETSGE TDSYGLPVRY
     DWAADYRGRA TVVYGHTPQA AVAELNNTIN IDTGCVFGGK LTAYRYPEKS FSEVKALQTY
     YEPAKPFLPE DAQAPLTEPQ RDHNILDIQD VLGKRVIGTR LYSNIMVREE NAMAALEVMS
     RFAADPRWLI YLPPTMSPTE TSHAEGMLEH PDEAFAYFRA RGVDRVVCEQ KHMGSRAVVI
     VCKDQAAAAA RFGVADGSAG ICYTRTGRHF FDNSDLEAAF LERLRQVLTR SGFWQDFTTD
     WVCLDCELMP WSAKAQALLT EQYAAVGRAG RVALDEAAAL LRQAAAHERL PRAVDREASG
     QNADIRALLQ RFTERSAMMH QYVEAYRSYC WPVDSIEDLR LAPFHILATE GKAHTDQNHL
     WHMNAVAKYC AGEDALFMPT NHIVVDVTKE EDTARGVAWW SDLTAAGGEG MVVKPCDFIV
     KNGRELLQPA VKCRGRKYLR IIYGPEYTLA ENLERLRQRG LGKKRSLALK EFALGVEALE
     RFVRQEPLHR IHECVFAVLA LESEPVDPRL
//