ID F7NXP1_9GAMM Unreviewed; 723 AA.
AC F7NXP1;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:EGM77289.1};
GN ORFNames=Rhein_2571 {ECO:0000313|EMBL:EGM77289.1};
OS Rheinheimera sp. A13L.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Rheinheimera.
OX NCBI_TaxID=506534 {ECO:0000313|EMBL:EGM77289.1, ECO:0000313|Proteomes:UP000004282};
RN [1] {ECO:0000313|EMBL:EGM77289.1, ECO:0000313|Proteomes:UP000004282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A13L {ECO:0000313|EMBL:EGM77289.1,
RC ECO:0000313|Proteomes:UP000004282};
RX PubMed=21742876; DOI=10.1128/JB.05636-11;
RA Gupta H.K., Gupta R.D., Singh A., Chauhan N.S., Sharma R.;
RT "Genome Sequence of Rheinheimera sp. Strain A13L, Isolated from Pangong
RT Lake, India.";
RL J. Bacteriol. 193:5873-5874(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM77289.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFHI01000023; EGM77289.1; -; Genomic_DNA.
DR RefSeq; WP_008899422.1; NZ_AFHI01000023.1.
DR AlphaFoldDB; F7NXP1; -.
DR STRING; 506534.Rhein_2571; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000004282; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 2.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..128
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 183..449
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
FT DOMAIN 483..656
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 723 AA; 81893 MW; F2BA0AF4240D99A4 CRC64;
MSLFLPIVPA LLWLIFLLSL ILIFLYYRLL FFTGLCCALS LWLWQVQQHQ LHTQQLLSLS
DPWLKGQVVS IRQQNEDFSR FLWQINEGPH QGYLLRLRWQ EAPQVLGQGQ HWWFKVRCKA
IRAPANPGSA YVEANAYVPG LIANCIVKDA VLLEPQWDHR QQLYQRLKAK IGDLPSFSLI
TALTLGERPF SDELWLGLQA TALGHLISIS GFHIGLLFGW VYGLMLLLAK INLSLLVCRQ
WAPFVALAAA WYYSLLAGFA IPTLRALVAL ILAVYLMQQH RRLSYSQSWL LVCGSLLLLN
PLWVMSISFW LTVYAVALIF LFVWRYPLLD HSFRGRVRHA IKFQALMTLL MSAPTLLFFH
GIAPLALLSN LIFVPWCSLL VIPYLLIALL LELVLPAHAV WHWQLADLIL APLYHWLLYG
AAMDYWWLLP AQTVFSALLV ALLLVAVFFL PGSAPRLRLS LLLLPFVFLL WPKGSQWQLH
MIDVGQGTAV LLQKGDRGLL YDVGPVYGSF NATQAYVLPY LHYQGIRQLD YLVLSHADSD
HTGAFSEVLK AYPQVRLIAD FQTGYPQQPC SALPAAYLDA RLWSFQSAYA KPKGNDSSCV
LAVEAVGWRF LLTGDISSKV EAELLSVQPD LKTDLLLLGH HGSKSSSHLR FLAQVQPLLA
LNSAAANNAY GHPSKEVRAR LSLLQIPLLN TADQGAIRIE ITEQQLHIWP YRQQPLPFWL
QKQ
//
