ID F7P0D2_9GAMM Unreviewed; 796 AA.
AC F7P0D2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=Rhein_3532 {ECO:0000313|EMBL:EGM76470.1};
OS Rheinheimera sp. A13L.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Rheinheimera.
OX NCBI_TaxID=506534 {ECO:0000313|EMBL:EGM76470.1, ECO:0000313|Proteomes:UP000004282};
RN [1] {ECO:0000313|EMBL:EGM76470.1, ECO:0000313|Proteomes:UP000004282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A13L {ECO:0000313|EMBL:EGM76470.1,
RC ECO:0000313|Proteomes:UP000004282};
RX PubMed=21742876; DOI=10.1128/JB.05636-11;
RA Gupta H.K., Gupta R.D., Singh A., Chauhan N.S., Sharma R.;
RT "Genome Sequence of Rheinheimera sp. Strain A13L, Isolated from Pangong
RT Lake, India.";
RL J. Bacteriol. 193:5873-5874(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM76470.1}.
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DR EMBL; AFHI01000056; EGM76470.1; -; Genomic_DNA.
DR RefSeq; WP_008900357.1; NZ_AFHI01000056.1.
DR AlphaFoldDB; F7P0D2; -.
DR STRING; 506534.Rhein_3532; -.
DR eggNOG; COG1067; Bacteria.
DR OrthoDB; 9758568at2; -.
DR Proteomes; UP000004282; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10046:SF49; LON PROTEASE HOMOLOG-RELATED; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 564..759
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT ACT_SITE 654
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 697
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 796 AA; 88832 MW; AC66BAA96C102CBB CRC64;
MTHNSHKYAL TAEHLGPQLD KNLIQQALDV SGLSSTFIGQ DRAKAALNFA IGMDMPGYNL
YVMGEPALGR YTLVQDILQQ AASEKATPDD WCYINNFDDE RIPGTLRLVP GEGKVLVKKV
EALIDELLDT FPAAFDNPGY QRKKKAIHQE FDDKYEAAIA LVERKALEQQ VVLYEENGAV
SFSPVVDGKA LDDNEFANLS EEKRQFFYDL VSELETILNE QLLELPQWKR ELSENLRALR
RETIEQAIKP LLKQLEHDYS AELGVLRYLR EMKPALVKAM LELLPEEAES DKLEELDIRG
IFVGDFVPNV LMHHELMDGA PIIFEPNPSY GNLFGRVEYS SMQGSLYTNY RMIRPGALHK
ANGGYLVLDA DRLLSQPSLW DALKLALKTG EILIDTLSDH AVTNSTIITP KAIPLSVKIV
LLGSRDLYYL VQDVDDEFNE LFRVLADFEH YLPFNEQTVR YMSLQIQDQI QQMDMETLSA
CGLKQLLNFS FRQAEHQRKL SARFAEVLEL VREACFYAAQ HDSAELRAEH VQMALEGKQY
RTGRISESFL EDIQEGQILI DTDDWAVGKI NGLTVLEIGD TAFGTPARIS TTVFAGSTGV
VDIEREVELG KSIHSKGVML LTGYLGAKYA QHFPLTLSAN IAMEQSYGLI DGDSASLAEV
CALISGIADI PITQSLAVTG SINQHGQVQA IGGVNEKIEG FFRLCESRGL TGKQGCIIPA
SNQLNLVLND EVIKAVEQGQ FHIYVVKGVD EALELLMDMP AGERNSKGQY PKRTINYLAL
RRLEEIAEIV NGSSDS
//
