ID F7PI79_9EURY Unreviewed; 413 AA.
AC F7PI79;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=FAD-dependent pyridine nucleotide-disulfide oxidoreductase {ECO:0000313|EMBL:CCQ32174.1};
DE SubName: Full=NADH oxidase protein {ECO:0000313|EMBL:ERJ05254.1};
DE EC=1.18.1.3 {ECO:0000313|EMBL:ERJ05254.1};
GN Name=noxA {ECO:0000313|EMBL:ERJ05254.1};
GN ORFNames=HLRTI_002766 {ECO:0000313|EMBL:ERJ05254.1}, HTIA_0022
GN {ECO:0000313|EMBL:CCQ32174.1};
OS Halorhabdus tiamatea SARL4B.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halorhabdus.
OX NCBI_TaxID=1033806 {ECO:0000313|EMBL:ERJ05254.1, ECO:0000313|Proteomes:UP000003861};
RN [1] {ECO:0000313|EMBL:ERJ05254.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ05254.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=21705593; DOI=10.1128/JB.05462-11;
RA Antunes A., Alam I., Bajic V.B., Stingl U.;
RT "Genome sequence of Halorhabdus tiamatea, the first archaeon isolated from
RT a deep-sea anoxic brine lake.";
RL J. Bacteriol. 193:4553-4554(2011).
RN [2] {ECO:0000313|EMBL:ERJ05254.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ05254.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=24324765;
RA Alam I., Antunes A., Kamau A.A., Ba Alawi W., Kalkatawi M., Stingl U.,
RA Bajic V.B.;
RT "INDIGO - INtegrated Data Warehouse of MIcrobial GenOmes with Examples from
RT the Red Sea Extremophiles.";
RL PLoS ONE 8:E82210-E82210(2013).
RN [3] {ECO:0000313|EMBL:CCQ32174.1, ECO:0000313|Proteomes:UP000015381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|Proteomes:UP000015381}, and Type strain:
RC SARL4B {ECO:0000313|EMBL:CCQ32174.1};
RX PubMed=24428220; DOI=10.1111/1462-2920.12393;
RA Werner J., Ferrer M., Michel G., Mann A.J., Huang S., Juarez S.,
RA Ciordia S., Albar J.P., Alcaide M., La Cono V., Yakimov M.M., Antunes A.,
RA Taborda M., Da Costa M.S., Amann R.I., Gloeckner F.O., Golyshina O.V.,
RA Golyshin P.N., Teeling H.;
RT "Halorhabdus tiamatea: proteogenomics and glycosidase activity measurements
RT identify the first cultivated euryarchaeon from a deep-sea anoxic brine
RT lake as potential polysaccharide degrader.";
RL Environ. Microbiol. 16:2525-2537(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; HF571520; CCQ32174.1; -; Genomic_DNA.
DR EMBL; AFNT02000039; ERJ05254.1; -; Genomic_DNA.
DR RefSeq; WP_008525278.1; NZ_AFNT02000039.1.
DR STRING; 1033806.HTIA_0022; -.
DR GeneID; 23798639; -.
DR KEGG; hti:HTIA_0022; -.
DR PATRIC; fig|1033806.12.peg.22; -.
DR eggNOG; arCOG01070; Archaea.
DR HOGENOM; CLU_003291_4_4_2; -.
DR OrthoDB; 28009at2157; -.
DR Proteomes; UP000003861; Unassembled WGS sequence.
DR Proteomes; UP000015381; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008860; F:ferredoxin-NAD+ reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR041575; Rubredoxin_C.
DR PANTHER; PTHR43429:SF3; NADH OXIDASE-RELATED; 1.
DR PANTHER; PTHR43429; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF18267; Rubredoxin_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ERJ05254.1}.
FT DOMAIN 4..283
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 335..387
FT /note="NADH-rubredoxin oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18267"
SQ SEQUENCE 413 AA; 45422 MW; 344DA958D29F58EB CRC64;
MTTSHVILGD GIAGSSAAET IREADPDADV TIITDEGEPL YNRILIKEFA KGTLPEEPVS
IHEEEWYEER DIDLELNTRV TSVDTDANVV EAQDGATYEY DKLLVATGGT PTRLPVENSD
AEGVHYFWTF KDARAIRDHA AEAETGVIVG AGLLGIDLAA ICGAQNVEAD YLMRGNRWWR
YALSLDGAEI IHEALRQKGV TPVFDSGVER FEVDDDGHVT GAVDANGEFH AGEFAAVAIG
LDFNTAFLED TAVELDDGIV VDEHMRTGVE DIYAAGDLTR YYDVILDERA QNGSWGSAKE
QGVVAAENMV ADEPVETFRY VSSYSITHFE FPFLSFGHPT IGDDEAERKY SDTEWRRLTF
KDGQLIGGVL IGDLSQQQAF KQIIREERPV ADQKEKLLEP DVDLDALPAP AVE
//
