ID F7PM11_9EURY Unreviewed; 640 AA.
AC F7PM11;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Metallo-beta-lactamase family protein, RNA-specific {ECO:0000313|EMBL:CCQ34548.1};
DE SubName: Full=mRNA 3'-end processing factor protein {ECO:0000313|EMBL:ERJ06380.1};
DE EC=3.1.27.- {ECO:0000313|EMBL:ERJ06380.1};
GN Name=epf2 {ECO:0000313|EMBL:ERJ06380.1};
GN ORFNames=HLRTI_001585 {ECO:0000313|EMBL:ERJ06380.1}, HTIA_2440
GN {ECO:0000313|EMBL:CCQ34548.1};
OS Halorhabdus tiamatea SARL4B.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halorhabdus.
OX NCBI_TaxID=1033806 {ECO:0000313|EMBL:ERJ06380.1, ECO:0000313|Proteomes:UP000003861};
RN [1] {ECO:0000313|EMBL:ERJ06380.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ06380.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=21705593; DOI=10.1128/JB.05462-11;
RA Antunes A., Alam I., Bajic V.B., Stingl U.;
RT "Genome sequence of Halorhabdus tiamatea, the first archaeon isolated from
RT a deep-sea anoxic brine lake.";
RL J. Bacteriol. 193:4553-4554(2011).
RN [2] {ECO:0000313|EMBL:ERJ06380.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ06380.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=24324765;
RA Alam I., Antunes A., Kamau A.A., Ba Alawi W., Kalkatawi M., Stingl U.,
RA Bajic V.B.;
RT "INDIGO - INtegrated Data Warehouse of MIcrobial GenOmes with Examples from
RT the Red Sea Extremophiles.";
RL PLoS ONE 8:E82210-E82210(2013).
RN [3] {ECO:0000313|EMBL:CCQ34548.1, ECO:0000313|Proteomes:UP000015381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|Proteomes:UP000015381}, and Type strain:
RC SARL4B {ECO:0000313|EMBL:CCQ34548.1};
RX PubMed=24428220; DOI=10.1111/1462-2920.12393;
RA Werner J., Ferrer M., Michel G., Mann A.J., Huang S., Juarez S.,
RA Ciordia S., Albar J.P., Alcaide M., La Cono V., Yakimov M.M., Antunes A.,
RA Taborda M., Da Costa M.S., Amann R.I., Gloeckner F.O., Golyshina O.V.,
RA Golyshin P.N., Teeling H.;
RT "Halorhabdus tiamatea: proteogenomics and glycosidase activity measurements
RT identify the first cultivated euryarchaeon from a deep-sea anoxic brine
RT lake as potential polysaccharide degrader.";
RL Environ. Microbiol. 16:2525-2537(2014).
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DR EMBL; HF571520; CCQ34548.1; -; Genomic_DNA.
DR EMBL; AFNT02000016; ERJ06380.1; -; Genomic_DNA.
DR RefSeq; WP_008527114.1; NZ_AFNT02000016.1.
DR STRING; 1033806.HTIA_2440; -.
DR GeneID; 23799015; -.
DR KEGG; hti:HTIA_2440; -.
DR PATRIC; fig|1033806.12.peg.2428; -.
DR eggNOG; arCOG00543; Archaea.
DR HOGENOM; CLU_009673_5_1_2; -.
DR OrthoDB; 7155at2157; -.
DR Proteomes; UP000003861; Unassembled WGS sequence.
DR Proteomes; UP000015381; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22532; KH-II_CPSF_arch_rpt1; 1.
DR CDD; cd02410; KH-II_CPSF_arch_rpt2; 1.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.30.300.20; -; 1.
DR Gene3D; 3.30.300.230; -; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR019975; aCPSF1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR033769; KH_arc.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR004044; KH_dom_type_2.
DR InterPro; IPR009019; KH_sf_prok-type.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR NCBIfam; TIGR03675; arCOG00543; 1.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF07650; KH_2; 1.
DR Pfam; PF17214; KH_7; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ERJ06380.1};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}.
FT DOMAIN 98..165
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 194..411
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 423..548
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 640 AA; 71782 MW; F0C87EE6E547A4C9 CRC64;
MSNVDQQLED TRETIVSEVP NDITITDVTY EGPELVIYTR DPKSFAENGD LVRRLASKLR
KRITVRPDTD VLAPPREARE EVLSVIPEEA TVTDLDFHED TGEVVIEAEK PGMVIGRHGS
TLREITQQVG WTPEVVRTPP IESSTVSNVR NFLKQEREDR RDILERVGRQ IHREEMSDDE
WVRITTLGCC REVGRAAFIL STPETRVLID AGDKPGAEDE YPYLQVPEAL GVGASSLDAV
VLTHAHLDHS ALIPLLFKYG YDGPIYTTEP TRDLMGLLTL DYLDVAAKEG RSPPYDSEMV
REAIKHTIPI EYGDVTDISP DIKLTLHNAG HILGSAVSHF HIGDGLYNVA FSGDIHYDDT
RLFNGAVNEF PRVETLVLES TYGGRNDYQT DQEDSEQRLK EIIRDTYEQG GSVLIPAFAV
GRSQELMLVL EEAMREGDIP EMPVHLDGMM WEATAIHTTY PEYLRDDLRD RIFHDDENPF
LADQFNHIDG GEEERQEVTD GEPAIVLSTS GMVTGGPIMS WLEHFGPDPD STLTFVGYQA
QGTLGRRIQN GWDEIPIGNN GRGRGNTLSL EMNVETVDGF SGHADRQGLE NFVKTMNPRP
EKVLCVHGDE SSVQDLSSAL YHEYNMRTFA PKNLETFRFV
//
