ID F7QKC6_9BRAD Unreviewed; 491 AA.
AC F7QKC6;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=4-hydroxyphenylacetate 3-monooxygenase {ECO:0000313|EMBL:EGP08295.1};
DE EC=1.14.14.9 {ECO:0000313|EMBL:EGP08295.1};
GN ORFNames=CSIRO_2021 {ECO:0000313|EMBL:EGP08295.1};
OS Bradyrhizobiaceae bacterium SG-6C.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae.
OX NCBI_TaxID=709797 {ECO:0000313|EMBL:EGP08295.1, ECO:0000313|Proteomes:UP000003148};
RN [1] {ECO:0000313|EMBL:EGP08295.1, ECO:0000313|Proteomes:UP000003148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG-6C {ECO:0000313|EMBL:EGP08295.1,
RC ECO:0000313|Proteomes:UP000003148};
RX PubMed=21742875; DOI=10.1128/JB.05647-11;
RA Pearce S.L., Pandey R., Dorrian S.J., Russell R.J., Oakeshott J.G.,
RA Pandey G.;
RT "Genome Sequence of the Newly Isolated Chemolithoautotrophic
RT Bradyrhizobiaceae Strain SG-6C.";
RL J. Bacteriol. 193:5057-5057(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGP08295.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFOF01000023; EGP08295.1; -; Genomic_DNA.
DR AlphaFoldDB; F7QKC6; -.
DR STRING; 709797.CSIRO_2021; -.
DR eggNOG; COG2368; Bacteria.
DR HOGENOM; CLU_023920_2_1_5; -.
DR Proteomes; UP000003148; Chromosome.
DR GO; GO:0052881; F:4-hydroxyphenylacetate 3-monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:EGP08295.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGP08295.1}.
FT DOMAIN 6..269
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 276..476
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 151..154
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 188
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 491 AA; 54300 MW; 504C51D12BACBD2B CRC64;
MMRSAKDYLS SLNDGRTIYI NGSAVDDVTT HHAFRNVATS MAGLFDFASA PANQELMTFD
NDGARANRIW QLPTSYAELV ERRKALEAWA SLHGGFMGRA PDHVASCISG LYMGLDVFKA
YDPARAGALE SYYRYARDND LYLTYVIINP QADRSKGAAE QADPFLTAGV VDKDAEGITI
RGAKMLATGG VVADEVFVTT IQPMRPGEER YAMSFAIPMN TKGLKMLSRK SYEDAAGAVF
DNPLSSRFDE NDSILYFDDV KVPWDRVFIE GNVEMCQKQF HATPCHVYQN YQAMVRLSVK
LKFLAGLAHR TAEMNGVTQF PQVREMLGQL AAETGMVDAL VAAMEAKGAH IGPYFIPHRH
TLYAAQVLTQ QLYSHIVNTL RELAGGGMIM LPSSITDFAN PEIASLIEKT QQSPKANSHD
RVKFYKLAWD AVGSEFGSRH QQYEMFYAGA TFVTKGHSYR TYDWAGSDAL VQRMLDSYDM
SGGIVSPSKA A
//
