ID F7UVE5_EEGSY Unreviewed; 461 AA.
AC F7UVE5;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN OrderedLocusNames=EGYY_20780 {ECO:0000313|EMBL:BAK45168.1};
OS Eggerthella sp. (strain YY7918).
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Eggerthella.
OX NCBI_TaxID=502558 {ECO:0000313|EMBL:BAK45168.1, ECO:0000313|Proteomes:UP000008929};
RN [1] {ECO:0000313|EMBL:BAK45168.1, ECO:0000313|Proteomes:UP000008929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YY7918 {ECO:0000313|EMBL:BAK45168.1,
RC ECO:0000313|Proteomes:UP000008929};
RX PubMed=21914883;
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete Genomic Sequence of the Equol-Producing Bacterium Eggerthella sp.
RT Strain YY7918, Isolated from Adult Human Intestine.";
RL J. Bacteriol. 193:5570-5571(2011).
RN [2] {ECO:0000313|Proteomes:UP000008929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YY7918 {ECO:0000313|Proteomes:UP000008929};
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete genome sequence of the equol-producing bacterium Eggerthella sp.
RT strain YY7918 isolated from adult human intestine.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR EMBL; AP012211; BAK45168.1; -; Genomic_DNA.
DR RefSeq; WP_013980412.1; NC_015738.1.
DR AlphaFoldDB; F7UVE5; -.
DR KEGG; eyy:EGYY_20780; -.
DR eggNOG; COG0733; Bacteria.
DR HOGENOM; CLU_006855_3_4_11; -.
DR Proteomes; UP000008929; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR CDD; cd10336; SLC6sbd_Tyt1-Like; 1.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR InterPro; IPR047218; YocR/YhdH-like.
DR NCBIfam; NF037979; Na_transp; 1.
DR PANTHER; PTHR42948; TRANSPORTER; 1.
DR PANTHER; PTHR42948:SF1; TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 2.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008929};
KW Symport {ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 49..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 461 AA; 48908 MW; 7729B8B41368821B CRC64;
MAIEGMPIVR SSWSGKWAFI LAAAASAVGL GNMWRFPYLA AKYGGGTFLI TYLVLVFTFG
VSLLLLETAL GRKTGQSAVG AFKQFGKKYA FIGILASAVP FIITPYYCII GGWVTKYAAA
YVINGPTALA DGGDFFSGFI TSNTESFLWM LVFMAIVFLI VSLGVKGGIE KANLFMMPAL
IVMAVGIAIY TLTMPGAIDG ALYYLVPDFS KFSPELVIGA LGQMFYSLSL AMGIMITYGS
YLDKKSSLTS SVARIGGFDI GVSFLAGLMI VPAAFVAMGS GEAVAANSGP SLMFITLPGV
FADMGNAAAI VGFLFFLLVL FAALTSAISL TETCVSIVQD GMGWQRRPAF LLVIGVITVA
GIFVNLGYNG LSFIEPLGAG SSLLDFFDFL SNSVIMPIVA LLTCVFVGWV IKPKAIIDEV
RISSRFRLAG AWTVIIKYVA PVLVVVILVA YVAQTFGLVS F
//
