ID F7UZY2_EEGSY Unreviewed; 659 AA.
AC F7UZY2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=FAD-dependent oxidoreductase 2 FAD binding domain-containing protein {ECO:0000259|Pfam:PF00890};
GN OrderedLocusNames=EGYY_08830 {ECO:0000313|EMBL:BAK44075.1};
OS Eggerthella sp. (strain YY7918).
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Eggerthella.
OX NCBI_TaxID=502558 {ECO:0000313|EMBL:BAK44075.1, ECO:0000313|Proteomes:UP000008929};
RN [1] {ECO:0000313|EMBL:BAK44075.1, ECO:0000313|Proteomes:UP000008929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YY7918 {ECO:0000313|EMBL:BAK44075.1,
RC ECO:0000313|Proteomes:UP000008929};
RX PubMed=21914883;
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete Genomic Sequence of the Equol-Producing Bacterium Eggerthella sp.
RT Strain YY7918, Isolated from Adult Human Intestine.";
RL J. Bacteriol. 193:5570-5571(2011).
RN [2] {ECO:0000313|Proteomes:UP000008929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YY7918 {ECO:0000313|Proteomes:UP000008929};
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete genome sequence of the equol-producing bacterium Eggerthella sp.
RT strain YY7918 isolated from adult human intestine.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; AP012211; BAK44075.1; -; Genomic_DNA.
DR RefSeq; WP_013979325.1; NC_015738.1.
DR AlphaFoldDB; F7UZY2; -.
DR STRING; 502558.EGYY_08830; -.
DR KEGG; eyy:EGYY_08830; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_011398_4_3_11; -.
DR Proteomes; UP000008929; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008929};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..659
FT /note="FAD-dependent oxidoreductase 2 FAD binding domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003369735"
FT DOMAIN 103..549
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 659 AA; 70374 MW; DB11A79A80A9E9B5 CRC64;
MAEMADGSKG FTRRNFMKGA LVTAAVASMG VVGTACAANG GEKAASGSAE GTSSATNDYT
NIYQGDVNLM PARKAECPGP RGPVAFESRE IPASDIQREE SFDVVVVGAG VGGLMAGLKA
ADMGANVLIL EKMTKGRGCF ECFGAVDARC QEGTEIDRVE LLDEIYRSAY YRTRPEPART
YVNRSGEATD FWQDILDKGA NGFVISKVEQ PPSTTGFPAL TPLIDTELGF YDSPALPPDA
GVRSGLSGIY VCMEMQDIAK NAYETVDLRF STPAVQLVSD ESGAVTGVIA RDESGYFKAN
AAKGVIMATG GYDCNPEMMQ AWTRPEDYAY SSWWNPGWGT TGDGHMMGLA IGAQMDPIPH
PVMNFRWGTP DSFADFRTWN AVYFGILVNG RGNRFVREDA PFQVVSNAQN AQPGYGKNCW
YIFDETMYEG MQDALDEFKE KGWLFEATTP AELAEATGID AEGLAATLER YNSFFKDGRD
QDFARDLMTT LPFTGSRLFA FTTNSNILAT GGGLCIDENC SVLNVNDEPI PGLFACGNAS
GSFFSGNYPR HIPGTSIGRA ITFGYVAAES AVNGTIGVGP KLDGNAPELT AYVDGSPVDD
DAKASFENMG PWNPYDPIHG SSTAYTPEQL GGISAACDNC HTYASGAETV ADGMKSLAD
//
