ID F7V6H0_CLOSS Unreviewed; 337 AA.
AC F7V6H0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CXIVA_23820 {ECO:0000313|EMBL:BAK48349.1};
OS Clostridium sp. (strain SY8519).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1042156 {ECO:0000313|EMBL:BAK48349.1, ECO:0000313|Proteomes:UP000008937};
RN [1] {ECO:0000313|Proteomes:UP000008937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY8519 {ECO:0000313|Proteomes:UP000008937};
RX PubMed=21914882; DOI=10.1128/JB.05637-11;
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete genomic sequence of the O-desmethylangolensin-producing bacterium
RT Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human
RT intestine.";
RL J. Bacteriol. 193:5568-5569(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; AP012212; BAK48349.1; -; Genomic_DNA.
DR RefSeq; WP_013978306.1; NC_015737.1.
DR AlphaFoldDB; F7V6H0; -.
DR STRING; 1042156.CXIVA_23820; -.
DR KEGG; cls:CXIVA_23820; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_0_9; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000008937; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF87; OCTAPRENYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000008937};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 337 AA; 37589 MW; 5D19073A6DB8E531 CRC64;
MKYLELAGLS EDMLQVEENL REFLDTGERS HALAEIIREQ LEIRGKRLRP LLVLLSGRLG
NPDSRTRSRL CKTAALIEMV HMASLIHDDI VDDSPLRRGR PSVQAKYGKD MAVYAGDFFL
SRILQILMRE NLTETGMLFG RTVESMCWGE IGQLAGYFDT SMTADRYLEN IYGKTVAVCE
LACVSGGREG GCSDETVGQL LQLGNSFGFL FQIRDDLLDF LSEEQAEGKP VHTDLREGIL
TLPVLCALEC DESREQITGL IERFHRGEGT DTEMQRLDAL IRQSGGMEQA VRIMENYGAA
AERSIRQLPA CDAREALAAV IQMLRLPDSI HKQGSVA
//
