ID F7V7J5_CLOSS Unreviewed; 558 AA.
AC F7V7J5;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Succinate dehydrogenase {ECO:0000313|EMBL:BAK46105.1};
GN Name=SdhA {ECO:0000313|EMBL:BAK46105.1};
GN OrderedLocusNames=CXIVA_01380 {ECO:0000313|EMBL:BAK46105.1};
OS Clostridium sp. (strain SY8519).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1042156 {ECO:0000313|EMBL:BAK46105.1, ECO:0000313|Proteomes:UP000008937};
RN [1] {ECO:0000313|Proteomes:UP000008937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY8519 {ECO:0000313|Proteomes:UP000008937};
RX PubMed=21914882; DOI=10.1128/JB.05637-11;
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete genomic sequence of the O-desmethylangolensin-producing bacterium
RT Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human
RT intestine.";
RL J. Bacteriol. 193:5568-5569(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; AP012212; BAK46105.1; -; Genomic_DNA.
DR RefSeq; WP_013976089.1; NC_015737.1.
DR AlphaFoldDB; F7V7J5; -.
DR STRING; 1042156.CXIVA_01380; -.
DR KEGG; cls:CXIVA_01380; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_8_2_9; -.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000008937; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR PANTHER; PTHR11632:SF82; FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008937}.
FT DOMAIN 15..223
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 449..553
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
SQ SEQUENCE 558 AA; 62213 MW; E9079BB5CB1DEB85 CRC64;
MQKQEIRQET ITAEVLVVGG GIGGLSAAVA IKEANPNADV LVVEKQTAGY AGKANKGGGV
LQYFDLEHIK PEDFVAYHAT SVGCFLGDQK RMYQYVSMNN EMLDRLESWG VKIPKKRVPT
GPMTYMIGVD LDITLQVRKT AQKLGVRFMD KTTVSDLLVT DGKIAGAVGY SILDGTFYVF
ESKLVILATG SQNYRVASMW SSGRGDGIAA AYRAGAQMRN PEFGNFSQLF RVRSNRECVF
GENVMYDAYG QNITKNFRRF PEADISSSAV AEWYRTMASG RGPVYLHTEE SEMTSNETMM
LHLWERPYGL KFWELDFEKA STVDKDQEVE CGLVGEQSPV KVDENYLTTI DGMYAIGDIS
YDGSCAPGAV PAPPGRNRGS GILNAVFAAL IAGGHAAKNI STRTQMPIDP EQVEKYKEDA
YAPLFRENGI NPKEVIGKVQ DLVCPAENTV IMSQNRLDVC IRKIEELKKL IPQMKASDFH
YLLTCHEAEA MVLSAEMQFR CASMRKESRG WFLREDYPEM DNQNWLKWIT CRNQDGEMVF
DTEDVPIADY PIKPPDIG
//
