ID F7VKR3_SORMK Unreviewed; 436 AA.
AC F7VKR3;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=COP9 signalosome complex subunit 4 {ECO:0000256|ARBA:ARBA00014881};
GN ORFNames=SMAC_00307 {ECO:0000313|EMBL:CCC06090.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC06090.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC06090.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC06090.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN4 family.
CC {ECO:0000256|ARBA:ARBA00010417}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC06090.1}.
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DR EMBL; CABT02000001; CCC06090.1; -; Genomic_DNA.
DR RefSeq; XP_003351763.1; XM_003351715.1.
DR AlphaFoldDB; F7VKR3; -.
DR STRING; 771870.F7VKR3; -.
DR GeneID; 10809351; -.
DR KEGG; smp:SMAC_00307; -.
DR VEuPathDB; FungiDB:SMAC_00307; -.
DR eggNOG; KOG1497; Eukaryota.
DR HOGENOM; CLU_028132_1_0_1; -.
DR InParanoid; F7VKR3; -.
DR OMA; KNIMHTV; -.
DR OrthoDB; 5476188at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040134; PSMD12/CSN4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR10855:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001881}.
FT DOMAIN 212..382
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 436 AA; 47592 MW; D67C344D11E8FCAD CRC64;
MASPELVEKL ALAQGMSQAE RPAFYKSIIN TWSANPDPDQ LTEDLIAITD SIFSEALGVV
ATRGLVIDLI DALKSLDPSV LTSKRISQVW LDVGKVIAEH ITSNPSLSTS LVDQTATIYE
DLIAAAHESQ NSFTEAAKTL AGIPLDASQR RVSDQYKAEL WIRIIRNFLE DDDATKAETY
LNKLKNIIHN VADANPVLNL HFKLSAARIQ DSNRQFLAAS QSYYDISLST AIAEDERLHT
LSMAIKCAVL APAGPPRSRV LGRLYKDDRS ASLEEYGILE KMFLDRLLTK AEVDKFAQGL
APHQLATTSD GSTVLAKAMV EHNLLAVSRL YRNIGFDALG SWLGLDSGNK AEEITARMIE
QGRLAGSIDQ IDRVIYFESG QEASGEKGSG RAEVPVGKEM RRQDGMVQAL AEGLERITDD
LLAEFPQLVP AGVPGN
//
