ID F7VNB4_SORMK Unreviewed; 306 AA.
AC F7VNB4;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=WGS project CABT00000000 data, contig 2.2 {ECO:0000313|EMBL:CCC06843.1};
GN ORFNames=SMAC_00871 {ECO:0000313|EMBL:CCC06843.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC06843.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC06843.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC06843.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC06843.1}.
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DR EMBL; CABT02000002; CCC06843.1; -; Genomic_DNA.
DR RefSeq; XP_003349980.1; XM_003349932.1.
DR AlphaFoldDB; F7VNB4; -.
DR STRING; 771870.F7VNB4; -.
DR GeneID; 10807493; -.
DR KEGG; smp:SMAC_00871; -.
DR VEuPathDB; FungiDB:SMAC_00871; -.
DR eggNOG; KOG0409; Eukaryota.
DR HOGENOM; CLU_035117_5_1_1; -.
DR InParanoid; F7VNB4; -.
DR OMA; AWVQSTT; -.
DR OrthoDB; 2715114at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580:SF3; 6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600); 1.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000001881}.
FT DOMAIN 6..162
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 177..292
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 179
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 306 AA; 33228 MW; 16C7658382613FC7 CRC64;
MTPRLFWIGL GNMGRGMSTN IVEKANLDQP LLIYNRTKQR CIDLSEKLPA GKTEIVDSIA
EGVSKADIIF NILSNDAVVE ASIAEILKND INGKLIVECS TIHPDTTERI AKQVEDAGAQ
FVAAPVFGAP AMADAGQLVG VLAGPKAAVD RARPYFKGVT AKAEVNMSDE PYRKALTLKL
IGNTFILNMV EQIAEGHVLA EKSGLGTEYL HQWIEGMFPG PYAAYSTRML TGDYYKRDYP
LFTVDLARKD AGHAMSLAKE AGVRLRNVET GDAHLAELKA HVGEKGDIAG IYGAVRMENG
LTYENE
//
