ID F7VS16_SORMK Unreviewed; 667 AA.
AC F7VS16;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Exocyst complex protein EXO70 {ECO:0000256|RuleBase:RU365026};
GN ORFNames=SMAC_01850 {ECO:0000313|EMBL:CCC08302.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC08302.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC08302.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC08302.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC complex which tethers secretory vesicles to the sites of exocytosis.
CC Also plays a role in the assembly of the exocyst.
CC {ECO:0000256|RuleBase:RU365026}.
CC -!- SUBCELLULAR LOCATION: Bud {ECO:0000256|RuleBase:RU365026}. Bud neck
CC {ECO:0000256|RuleBase:RU365026}.
CC -!- SIMILARITY: Belongs to the EXO70 family.
CC {ECO:0000256|ARBA:ARBA00006756, ECO:0000256|RuleBase:RU365026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC08302.1}.
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DR EMBL; CABT02000005; CCC08302.1; -; Genomic_DNA.
DR RefSeq; XP_003348827.1; XM_003348779.1.
DR AlphaFoldDB; F7VS16; -.
DR STRING; 771870.F7VS16; -.
DR GeneID; 10806289; -.
DR KEGG; smp:SMAC_01850; -.
DR VEuPathDB; FungiDB:SMAC_01850; -.
DR eggNOG; KOG2344; Eukaryota.
DR HOGENOM; CLU_010236_4_2_1; -.
DR InParanoid; F7VS16; -.
DR OMA; GIIRAGP; -.
DR OrthoDB; 460764at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR GO; GO:0000145; C:exocyst; IEA:InterPro.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1280.170; Exocyst complex component Exo70; 1.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR004140; Exo70.
DR InterPro; IPR046364; Exo70_C.
DR PANTHER; PTHR12542:SF41; EXOCYST COMPLEX COMPONENT 7; 1.
DR PANTHER; PTHR12542; EXOCYST COMPLEX PROTEIN EXO70; 1.
DR Pfam; PF03081; Exo70_C; 1.
DR Pfam; PF20669; Exo70_N; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365026};
KW Protein transport {ECO:0000256|RuleBase:RU365026};
KW Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365026}.
FT DOMAIN 279..663
FT /note="Exocyst complex subunit Exo70 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03081"
SQ SEQUENCE 667 AA; 73590 MW; 66853ABA3881344E CRC64;
MAVGLINGRL AADEEARAEV DVLNSRLEKT SQLTKKIQAC LGRLDATGKS VRDVAGPLSG
ETKKLQVLGN SKSPGRHISL YDVVHRQWTL TDSHSCLDID AVIAAIEKLR SPADSKNDEE
QIIRMGPEKA GLSNYLASIK RLNKALNDMK ASNLRSTQQT VADLQRLVKT GNSQLESSFD
KLLRSETPRA IEPLHYLTKN MPFPVLSQEK ITRLGLMNSY LTGVHQQNTG AGSSQESPVI
KIYAEVRSQY LLSTLGNLAT ASTNTAKKKT PEAVYRAGTN GMGTYAQAME GLFLSEYDNI
CSIFMREDWG PVFQATCQPA LVELGRTLRE LNSHIKSHIT TDCFLAYEIV EIISSLSNNL
ESRTGELKSS LAAALKPIRE TAKSSLVDLL EETKRQVNSL QSLPADGAPT QLASQTMQRL
QSMVDFLRPI SSIMISIGDG GWKSAAASKG GATDTIPSLS SFDVGADGQD IFTHYCADTI
ETLLSSLDAR ARVLLQQKKA VIGVFLANNV TIIERMIMES GLATLLQSRL QVLEVWRKKS
AALYTETCKE ISIHLFDTVH TNRTARPTSG QGMVSSASIM KGLSSKDKEK IKGMFTAFNS
GFEEMVARHK QFAMEKEVRQ MLAQDVQHML EPLYNRFWDR YHEIDKGKGK YVKYDKGSIA
AVFRSLY
//
