ID   F7VS49_SORMK            Unreviewed;       689 AA.
AC   F7VS49;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=WGS project CABT00000000 data, contig 2.5 {ECO:0000313|EMBL:CCC08335.1};
GN   ORFNames=SMAC_01882 {ECO:0000313|EMBL:CCC08335.1};
OS   Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX   NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC08335.1, ECO:0000313|Proteomes:UP000001881};
RN   [1] {ECO:0000313|EMBL:CCC08335.1, ECO:0000313|Proteomes:UP000001881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC   {ECO:0000313|Proteomes:UP000001881};
RC   TISSUE=Mycelium {ECO:0000313|EMBL:CCC08335.1};
RX   PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA   Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA   Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA   Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT   "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT   Sordaria macrospora, a model organism for fungal morphogenesis.";
RL   PLoS Genet. 6:E1000891-E1000891(2010).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCC08335.1}.
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DR   EMBL; CABT02000005; CCC08335.1; -; Genomic_DNA.
DR   RefSeq; XP_003348859.1; XM_003348811.1.
DR   AlphaFoldDB; F7VS49; -.
DR   STRING; 771870.F7VS49; -.
DR   GeneID; 10806320; -.
DR   KEGG; smp:SMAC_01882; -.
DR   VEuPathDB; FungiDB:SMAC_01882; -.
DR   eggNOG; KOG1175; Eukaryota.
DR   HOGENOM; CLU_000022_3_3_1; -.
DR   InParanoid; F7VS49; -.
DR   OMA; MPNTWQT; -.
DR   OrthoDB; 45466at2759; -.
DR   Proteomes; UP000001881; Unassembled WGS sequence.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001881}.
FT   DOMAIN          36..93
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          103..445
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          575..646
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   689 AA;  75379 MW;  4BE0134343843A59 CRC64;
     MTVTNELWRH QDPQSTQMWK FIEHVNSKYG LQLNDYPSLY KWSVDNVAAF WEEAWHFTGI
     RSSKLFGEVL PENAPMFPRP DFFAGARLNF AENLLFPGNA DVNGSDVAVI TATENDEHLT
     ETTWDQLREQ VRQCSNALRA AGVKENSVVA GFVANHVQAL VALLSAATLG AIWTGISPDN
     GVSAVLDRLV QIKPTVLFSD NATLYNGKEW SGIPKTLEVV EELQKHGLEL VVVVKGLKNF
     ETGLNKIRAK GVKAEEYDEF LHSSPKEEPL VFAQLPPSHP LYVLYSSGTT GLPKAIVHTA
     AGTLLQHKKE LFIHSNLSPG SRMLYYTTTS WMMHHWSVSS LSCGASLVLY SGSPFRPHGH
     LSLPRLLSSL KVTHFGTSAA YLTTLEANNV RPIDPEHNLD LSSLEAIYST AAPLPPSTFA
     FVYTAFPATI NLASITGGTD IISLFGAPCP LLPVRAGEVQ CAGLGMAISV MDSASDASNP
     LPVDPVGSEG DLVCLKPFPC QPLTFFGPGG DDKYRAAYFE RFGTAMWHHG DFVRMDPSTG
     ALVMLGRSDG VLKPAGVRFG SAEIYNVLTR FFASEVEDAV CVGRRREFDR DETVCLFVVM
     VPGKQFSSEV RDRIKNVIKR ELSPRHVPGV VEECGPAGIP RTGNGKKIEV AVKQILSGLK
     VKTNASVANP EALEWFRSWA KAVEEPLPN
//