ID F7W8P5_SORMK Unreviewed; 545 AA.
AC F7W8P5;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=WGS project CABT00000000 data, contig 2.46 {ECO:0000313|EMBL:CCC13831.1};
GN ORFNames=SMAC_07467 {ECO:0000313|EMBL:CCC13831.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC13831.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC13831.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC13831.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M67C family.
CC {ECO:0000256|ARBA:ARBA00010981}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC13831.1}.
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DR EMBL; CABT02000046; CCC13831.1; -; Genomic_DNA.
DR RefSeq; XP_003345480.1; XM_003345432.1.
DR AlphaFoldDB; F7W8P5; -.
DR STRING; 771870.F7W8P5; -.
DR MEROPS; M67.A06; -.
DR GeneID; 10802825; -.
DR KEGG; smp:SMAC_07467; -.
DR VEuPathDB; FungiDB:SMAC_07467; -.
DR eggNOG; KOG2880; Eukaryota.
DR HOGENOM; CLU_023304_4_0_1; -.
DR InParanoid; F7W8P5; -.
DR OMA; SWGVFRL; -.
DR OrthoDB; 5490729at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0061578; F:K63-linked deubiquitinase activity; IEA:InterPro.
DR GO; GO:0140492; F:metal-dependent deubiquitinase activity; IEA:InterPro.
DR CDD; cd08066; MPN_AMSH_like; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR044098; STAMBP/STALP-like_MPN.
DR InterPro; IPR015063; USP8_dimer.
DR PANTHER; PTHR12947; AMSH-LIKE PROTEASE; 1.
DR PANTHER; PTHR12947:SF13; FI19924P1; 1.
DR Pfam; PF01398; JAB; 1.
DR Pfam; PF08969; USP8_dimer; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR SUPFAM; SSF140856; USP8 N-terminal domain-like; 1.
DR PROSITE; PS50249; MPN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 357..487
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
FT REGION 180..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 89..120
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 180..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..284
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 62412 MW; C8FAB324B817A634 CRC64;
MGSATIEAGS RPMNVKEISE KAKQYDWNPR IGFKFWARAA NTIHHEGQIY LHEGSIAQAY
MFLLRYCTLV LEDMAKHPEA KLPENRALMR QLNNRINNVV EQLEQLKPQI EEAYHKWQQL
TASVEDSREK RRSTSSQYAR HAASDAALSW NHISQAKILD AGSNQELAVD LARETLLKRR
RRRRQENDEE DERTRRTYAG YREENGYGVD RRQQYPTPPP TNNRYSEDDD LRRQMEATRR
QLDRSGGYGT SETDNGPPLP PKVIPFERPI PVTRPPPPPP RPRKESGSFG RDGRRNGILP
SQTIRLVTDE DDVDDRPARP PKVSEPPPEA EEKPKEANKV TFRPVAYLES GEPLRSVFLP
SSLRRRFLEL ARENTIRELE MCGILCGTLI NNALFITCLL IPEQECTSDT CETINEEAYV
TYCIENDLLV LGWIHTHPTQ TCFMSSRDLH THAGYQTMMK ESIAIVCAPR YDPSYGIFRL
TDPPGLPHII NCNTPGVFHQ HGIPSDEIYC SARHAPGHVF ESSRVDFEVV DLRPEGSKVP
AFRRY
//
