ID   F7W965_SORMK            Unreviewed;       424 AA.
AC   F7W965;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=WGS project CABT00000000 data, contig 2.49 {ECO:0000313|EMBL:CCC05145.1};
GN   ORFNames=SMAC_07882 {ECO:0000313|EMBL:CCC05145.1};
OS   Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX   NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC05145.1, ECO:0000313|Proteomes:UP000001881};
RN   [1] {ECO:0000313|EMBL:CCC05145.1, ECO:0000313|Proteomes:UP000001881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC   {ECO:0000313|Proteomes:UP000001881};
RC   TISSUE=Mycelium {ECO:0000313|EMBL:CCC05145.1};
RX   PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA   Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA   Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA   Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT   "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT   Sordaria macrospora, a model organism for fungal morphogenesis.";
RL   PLoS Genet. 6:E1000891-E1000891(2010).
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCC05145.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CABT02000049; CCC05145.1; -; Genomic_DNA.
DR   RefSeq; XP_003345206.1; XM_003345158.1.
DR   AlphaFoldDB; F7W965; -.
DR   STRING; 771870.F7W965; -.
DR   GeneID; 10802522; -.
DR   KEGG; smp:SMAC_07882; -.
DR   VEuPathDB; FungiDB:SMAC_07882; -.
DR   eggNOG; ENOG502QQNB; Eukaryota.
DR   HOGENOM; CLU_033094_0_0_1; -.
DR   InParanoid; F7W965; -.
DR   OMA; DTVFVPW; -.
DR   OrthoDB; 4215at2759; -.
DR   Proteomes; UP000001881; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd03507; Delta12-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR021863; FAS_N.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR32100:SF19; BIFUNCTIONAL OELATE_LINOLEIC ACID DELTA DESATURASE (EUROFUNG); 1.
DR   PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR   Pfam; PF11960; DUF3474; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        68..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          47..79
FT                   /note="Fatty acid desaturase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11960"
FT   DOMAIN          99..383
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   424 AA;  48598 MW;  1E4B7297C5739B85 CRC64;
     MTVTTRSHKA TAEPEVVSAT TSGSDFSSAS SVTSEKTSEA IEYPDIKTIR DAIPDHCFRP
     RVWISMSYFF RDFAMAFGLG YLAWQYIPQI ASTPLRYGAW AAYGYLQGLI CTGIWILAHE
     CGHGAFSRHV WFNNVIGWIG HSFLLVPYFS WKFSHHRHHR FTGHMEKDMA FVPATAADRN
     QRKLANLYMD KETAEMFEDV PIVQLVKLIA HQLAGWQMYL LFNVSAGKAS KQWETGKGGM
     GWLRVSHFEP TSAVFRNSEA IYIALSDLGL MIMGYILYSA AQVVGWQMVG LLYFQQYFWV
     HHWLVAITYL HHTHEEVHHF DADSWTFVKG ALATVDRDFG FIGKHLFHNI IDHHVVHHLF
     PRIPFYYAEE ATNSIRPMLG PLYHRDDRSF MGQLWHSFTT CKFVVPDPKV PGALVWAHTV
     QGTQ
//