ID   F7XM89_METZD            Unreviewed;       496 AA.
AC   F7XM89;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Dihydropteroate synthase-related protein {ECO:0000313|EMBL:AEH60978.1};
GN   OrderedLocusNames=Mzhil_1122 {ECO:0000313|EMBL:AEH60978.1};
OS   Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)
OS   (Methanohalophilus zhilinae).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosalsum.
OX   NCBI_TaxID=679901 {ECO:0000313|EMBL:AEH60978.1, ECO:0000313|Proteomes:UP000006622};
RN   [1] {ECO:0000313|Proteomes:UP000006622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4017 / NBRC 107636 / OCM 62 / WeN5
RC   {ECO:0000313|Proteomes:UP000006622};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ovchinnikova G., Daligault H., Detter J.C., Han C., Tapia R., Larimer F.,
RA   Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA   Wu D., Spring S., Schueler E., Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanosalsum zhilinae DSM 4017.";
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002101; AEH60978.1; -; Genomic_DNA.
DR   RefSeq; WP_013898415.1; NC_015676.1.
DR   AlphaFoldDB; F7XM89; -.
DR   STRING; 679901.Mzhil_1122; -.
DR   GeneID; 10822750; -.
DR   KEGG; mzh:Mzhil_1122; -.
DR   HOGENOM; CLU_041129_0_0_2; -.
DR   OrthoDB; 70327at2157; -.
DR   Proteomes; UP000006622; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR045031; DHP_synth-like.
DR   InterPro; IPR005236; Dihydropt_synth.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR025595; DUF4346.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   NCBIfam; TIGR00284; dihydropteroate synthase-like protein; 1.
DR   PANTHER; PTHR20941; FOLATE SYNTHESIS PROTEINS; 1.
DR   PANTHER; PTHR20941:SF1; FOLIC ACID SYNTHESIS PROTEIN FOL1; 1.
DR   Pfam; PF14251; DUF4346; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006622}.
FT   DOMAIN          131..366
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
SQ   SEQUENCE   496 AA;  54007 MW;  A133E4A3B57770C5 CRC64;
     MKILVATGRQ AEETVRKSVK SRADVLIVDT DIAAFITPSR LLVALMDQKP NTYDILFVPG
     LASGDFSIVE KKMDCKVYLG PKHAYDLGYV LDFVEDFEFS KNVPACELLS DIRKKLAIDK
     VSDLEDRSVP QLLINDLKIG GSSRMKVMAE IVDSTSMSKE LLISKIEEFV KKGADIIDLG
     SSMNATPEEV KSTVKTARSV SSVPISIDTL EPDLIKTALE GGVDIVLSLN GSNIDQVGKH
     VAFHTATAVI IPDSDGDIGS LANNIKKAKN FGIKYIIADP VLDPVGHGIT RSIVRYYEFS
     KDFPDIPLFF GSGNVTELID ADSIGVNAVL CGIASELGAA ILFTPEYSDK THGSIEELTT
     ASMMMTVACE RNSSPKDLGI DLLKLKEKRK RIEADLCEDP LFAVESESWE LDPKGPVKIG
     IVSRSRYSDS SFKGSLIIAQ HKRACVVGKT ASSVLNTLIE KGLVSTLEHA GYLGRELARA
     ELAIKYDRSY AQDDDF
//