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Database: UniProt
Entry: F7YHT4_VIBA7
LinkDB: F7YHT4_VIBA7
Original site: F7YHT4_VIBA7 
ID   F7YHT4_VIBA7            Unreviewed;       471 AA.
AC   F7YHT4;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 53.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=VAA_00846 {ECO:0000313|EMBL:AEH31802.1};
OS   Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=882102 {ECO:0000313|EMBL:AEH31802.1, ECO:0000313|Proteomes:UP000006800};
RN   [1] {ECO:0000313|EMBL:AEH31802.1, ECO:0000313|Proteomes:UP000006800}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 68554 / 775 {ECO:0000313|Proteomes:UP000006800};
RX   PubMed=21576332; DOI=10.1128/IAI.05138-11;
RA   Naka H., Dias G.M., Thompson C.C., Dubay C., Thompson F.L.,
RA   Crosa J.H.;
RT   "Complete genome sequence of the marine fish pathogen Vibrio
RT   anguillarum harboring the pJM1 virulence plasmid and genomic
RT   comparison with other virulent strains of V. anguillarum and V.
RT   ordalii.";
RL   Infect. Immun. 79:2889-2900(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP002284; AEH31802.1; -; Genomic_DNA.
DR   STRING; 882102.VAA_00846; -.
DR   EnsemblBacteria; AEH31802; AEH31802; VAA_00846.
DR   KEGG; van:VAA_00846; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   Proteomes; UP000006800; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006800};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      168    381       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      379    448       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     176    183       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      330    350       {ECO:0000256|SAM:Coils}.
FT   COILED      448    468       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   471 AA;  53489 MW;  29620A06C9981458 CRC64;
     MRATVSSSLW LQCLQQLQEE LPAAEFSMWV RPLQAELNDN TLTLFAPNRF VLDWVRDKYI
     NSINRLLQEH CGHDTPNLRF EVGSRRVSAP KAAPVRTQAD VAAESSAPAQ LQARKPVHRT
     WENDTVVADI NHRSNVNPKH KFNNFVEGKS NQLGLAAARQ VSDNPGAAYN PLFLYGGTGL
     GKTHLLHAVG NAIVDNNPNA KVIYMHSERF VQDMVKALQN NAIEEFKRYY RSVDALLIDD
     IQFFANKERS QEEFFHTFNA LLEGNQQIIL TSDRYPKEIN GVEDRLKSRF GWGLTVAIEP
     PELETRVAIL MKKAEDHQIH LADEVAFFIA KRLRSNVREL EGALNRVIAN ANFTGRPITI
     DFVREALRDL LALQEKLVTI DNIQKTVAEY YKIKVADLLS KRRSRSVARP RQLAMALAKE
     LTNHSLPEIG DAFGGRDHTT VLHACRKIQQ LREESHDIKE DYSNLIRTLS S
//
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