ID F7YUI0_9THEM Unreviewed; 328 AA.
AC F7YUI0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:AEH51451.1};
GN ORFNames=Theth_1389 {ECO:0000313|EMBL:AEH51451.1};
OS Pseudothermotoga thermarum DSM 5069.
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Pseudothermotoga.
OX NCBI_TaxID=688269 {ECO:0000313|EMBL:AEH51451.1, ECO:0000313|Proteomes:UP000006804};
RN [1] {ECO:0000313|EMBL:AEH51451.1, ECO:0000313|Proteomes:UP000006804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5069 {ECO:0000313|EMBL:AEH51451.1,
RC ECO:0000313|Proteomes:UP000006804};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Thermotoga thermarum DSM 5069.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002351; AEH51451.1; -; Genomic_DNA.
DR RefSeq; WP_013932665.1; NC_015707.1.
DR AlphaFoldDB; F7YUI0; -.
DR STRING; 688269.Theth_1389; -.
DR KEGG; tta:Theth_1389; -.
DR PATRIC; fig|688269.3.peg.1431; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_0; -.
DR OrthoDB; 47944at2; -.
DR Proteomes; UP000006804; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006804};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 328 AA; 37318 MW; A9BDCB61D24B7F01 CRC64;
MKKFVTISDV AKEAGVSINT VSRVLNNKPD VSPETRKKVL EAAKKLGYIK NATASCFRRS
VSKTIGVVFE DSSNPFYTEV FKGIEMRARG YGYQVILMNT ERDYVNELKA VDTLLEKRVD
GIIISPTQFA QEDIEKLLKL NFPFVILGVH FEGLNVDEVY SDDVKGGYLA TKHLLEKGRR
KILMLNAYMY KSVARMRYEG YLKAHKEFGI EPFEMVEIEE GYESAFNKIM ELSNLDYDAI
FCFNDVFAIA CLKALKALKR NVPEDVAIVG YDDISYASFV QPSLTTVRID KHIEGMIAFD
LLYEKITEQR SSPKQIVLDV ELIVREST
//
