ID F8AAZ8_THEID Unreviewed; 647 AA.
AC F8AAZ8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Transketolase domain-containing protein {ECO:0000313|EMBL:AEH44364.1};
GN OrderedLocusNames=Thein_0482 {ECO:0000313|EMBL:AEH44364.1};
OS Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812).
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfatatoraceae; Thermodesulfatator.
OX NCBI_TaxID=667014 {ECO:0000313|EMBL:AEH44364.1, ECO:0000313|Proteomes:UP000006793};
RN [1] {ECO:0000313|Proteomes:UP000006793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15286 / JCM 11887 / CIR29812
RC {ECO:0000313|Proteomes:UP000006793};
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders L.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Thermodesulfatator indicus DSM 15286.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEH44364.1, ECO:0000313|Proteomes:UP000006793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15286 / JCM 11887 / CIR29812
RC {ECO:0000313|Proteomes:UP000006793};
RX PubMed=22768359; DOI=10.4056/sigs.2665915;
RA Anderson I., Saunders E., Lapidus A., Nolan M., Lucas S., Tice H.,
RA Del Rio T.G., Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S.,
RA Liolios K., Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Chang Y.J.,
RA Brambilla E.M., Rohde M., Spring S., Goker M., Detter J.C., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P.;
RT "Complete genome sequence of the thermophilic sulfate-reducing ocean
RT bacterium Thermodesulfatator indicus type strain (CIR29812(T)).";
RL Stand. Genomic Sci. 6:155-164(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
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DR EMBL; CP002683; AEH44364.1; -; Genomic_DNA.
DR RefSeq; WP_013907109.1; NC_015681.1.
DR AlphaFoldDB; F8AAZ8; -.
DR STRING; 667014.Thein_0482; -.
DR PaxDb; 667014-Thein_0482; -.
DR KEGG; tid:Thein_0482; -.
DR PATRIC; fig|667014.3.peg.500; -.
DR eggNOG; COG0021; Bacteria.
DR HOGENOM; CLU_009227_3_1_0; -.
DR InParanoid; F8AAZ8; -.
DR OrthoDB; 8732661at2; -.
DR Proteomes; UP000006793; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016744; F:transketolase or transaldolase activity; IEA:UniProt.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR CDD; cd02012; TPP_TK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR InterPro; IPR005474; Transketolase_N.
DR PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006793}.
FT DOMAIN 330..500
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 647 AA; 71253 MW; 08AB6F62E46C9B1C CRC64;
MFKIDLSKER LSQEEIKTLE EMWRRCARRI ILSTTLAGCG HPGGSLSSLH MLILLYALIE
HDPKNPRFPE RDRVVISHGH ISPGVYSVLC EYGYFPEEPF LMEFRRAGSA FGGHVEQSVP
GVEWNTGNLG QGLSAACGMA RALKLKEIPR RVFCVMGDGE QQKGQVIEAR RFAVKFGLNN
LCALIDYNRL QIGGRIYRVM PQDIAHEIKA TFWNVIEANG HDFNDLYQAL RRFVTGEVLC
PEKPTAILAQ TTMGKGISFM EDDEKWHGMA LPPDLAKKAL EELGFDPSEV DVLLEKRKSY
EISFPVFPHE PEPVEVEVGE PILYGPEVKT DCRSAYGKAL ASLAELNNKK GEPPKVLGVS
CDLEGSVKMT AFRKISPLAF HEVGIQEHHA ATVAGVLSKE GFLTFFSTFG VFAVDETINQ
HRLNVLNETA LKIVATHCGL DVGEDGPTHQ CVDYLGLLLN LIGLEIYFPA DPNQTDRIIR
YVAKSKGNVF VGMGRSKLPV ILNEAGEPFF GKDYVFTPGK ADLLREGEEG TIIAFGSVMP
QVLSAWEKLK SEGVSVSVLN MASLRPLDEK AILNAAEQGP IMVVEDHVVE TGLGSLVAKT
LAKHGQSAKL CLKGVTRYGT SGKPADLYRE QGLDADSIVK DMKELLA
//
