ID F8C286_THEGP Unreviewed; 508 AA.
AC F8C286;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Acyl-(Acyl-carrier-protein)--phospholipid O-acyltransferase {ECO:0000313|EMBL:AEH23344.1};
DE EC=2.3.1.40 {ECO:0000313|EMBL:AEH23344.1};
GN OrderedLocusNames=TOPB45_1263 {ECO:0000313|EMBL:AEH23344.1};
OS Thermodesulfobacterium geofontis (strain OPF15).
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae;
OC Thermodesulfobacterium.
OX NCBI_TaxID=795359 {ECO:0000313|EMBL:AEH23344.1, ECO:0000313|Proteomes:UP000006583};
RN [1] {ECO:0000313|EMBL:AEH23344.1, ECO:0000313|Proteomes:UP000006583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OPF15 {ECO:0000313|EMBL:AEH23344.1,
RC ECO:0000313|Proteomes:UP000006583};
RX PubMed=23580711; DOI=10.1128/genomea.00162-13;
RA Elkins J.G., Hamilton-Brehm S.D., Lucas S., Han J., Lapidus A., Cheng J.F.,
RA Goodwin L.A., Pitluck S., Peters L., Mikhailova N., Davenport K.W.,
RA Detter J.C., Han C.S., Tapia R., Land M.L., Hauser L., Kyrpides N.C.,
RA Ivanova N.N., Pagani I., Bruce D., Woyke T., Cottingham R.W.;
RT "Complete genome sequence of the hyperthermophilic sulfate-reducing
RT bacterium Thermodesulfobacterium geofontis OPF15T.";
RL Genome Announc. 1:E0016213-E0016213(2013).
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DR EMBL; CP002829; AEH23344.1; -; Genomic_DNA.
DR AlphaFoldDB; F8C286; -.
DR STRING; 795359.TOPB45_1263; -.
DR KEGG; top:TOPB45_1263; -.
DR PATRIC; fig|795359.3.peg.1284; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_8_0; -.
DR OrthoDB; 9799237at2; -.
DR Proteomes; UP000006583; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008779; F:acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:AEH23344.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006583};
KW Transferase {ECO:0000313|EMBL:AEH23344.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..368
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 428..490
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 508 AA; 57817 MW; 67DE53A4E1DE8BA8 CRC64;
MQLHEKFIYT AKTYSNKIAI VDKLIEKRFT YQQTLIASLI FSRKIKRFRE RLIGIMLPNS
AVAIFTVIGT LMAEKIPVML NYSTGAEYNL KYAREKCNFR TVITSQKLLE RVNCPILENM
EFVENWIEEI DLKEKVIASF ISKLPLKFLM SYCGVDGDPE KTAVILFTSG TEKDPKAVEL
SHKNILSNIE GFSQMAKLTE KDVIMSILPY FHVFGLTVNL WTPLYHGMTL ITYPTPLDYQ
KICQIVKGEK PTLMAATPSF WWGYLKKSEP GTFDSLRLMI SGADKCPQPL RDTFWEKHKK
LLLEGYGTTE TSPVISVNMP DAYKPGSVGK PLPNLEVMIE NYETGEKCGP NEIGRILVRG
PNVMKGYFND LEETSMRIRH GWYDTGDMGY LDEDGYLWHV GRLKRFVKIG GEMISLVKVE
DELEKVLPKN VECCVVEIPD EVKGAKIVAV VSQKIDEKAI LKQLAKVLPN LAIPKHFVVM
EDLPKMGSGK IDFRKVQELI MEKLGLKV
//
