ID F8C4P7_THEGP Unreviewed; 274 AA.
AC F8C4P7;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:AEH22717.1};
GN OrderedLocusNames=TOPB45_0615 {ECO:0000313|EMBL:AEH22717.1};
OS Thermodesulfobacterium geofontis (strain OPF15).
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae;
OC Thermodesulfobacterium.
OX NCBI_TaxID=795359 {ECO:0000313|EMBL:AEH22717.1, ECO:0000313|Proteomes:UP000006583};
RN [1] {ECO:0000313|EMBL:AEH22717.1, ECO:0000313|Proteomes:UP000006583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OPF15 {ECO:0000313|EMBL:AEH22717.1,
RC ECO:0000313|Proteomes:UP000006583};
RX PubMed=23580711; DOI=10.1128/genomea.00162-13;
RA Elkins J.G., Hamilton-Brehm S.D., Lucas S., Han J., Lapidus A., Cheng J.F.,
RA Goodwin L.A., Pitluck S., Peters L., Mikhailova N., Davenport K.W.,
RA Detter J.C., Han C.S., Tapia R., Land M.L., Hauser L., Kyrpides N.C.,
RA Ivanova N.N., Pagani I., Bruce D., Woyke T., Cottingham R.W.;
RT "Complete genome sequence of the hyperthermophilic sulfate-reducing
RT bacterium Thermodesulfobacterium geofontis OPF15T.";
RL Genome Announc. 1:E0016213-E0016213(2013).
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DR EMBL; CP002829; AEH22717.1; -; Genomic_DNA.
DR RefSeq; WP_013909417.1; NC_015682.1.
DR AlphaFoldDB; F8C4P7; -.
DR STRING; 795359.TOPB45_0615; -.
DR KEGG; top:TOPB45_0615; -.
DR PATRIC; fig|795359.3.peg.625; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_036672_1_1_0; -.
DR OrthoDB; 9800497at2; -.
DR Proteomes; UP000006583; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006583}.
FT DOMAIN 5..270
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 274 AA; 31718 MW; 6C662782C790A1F6 CRC64;
MDENFRVGII GGKGKMGNFF KNFFEKKGYP VEVSDVNTTL TNIELVKRNK IILISVPIEI
FPEVVKEISS FVRETHWVID ICSLKNEPVK VMKKFLKKGE ILATHPLFGP YEEDLKGKTI
AFYPVRGKEI VKWFKNLMSS EGLNLVKISP KKHDEIMALV QVINHFWLIL LAKTIKDSGF
NLKDLIYLST PSFLRQLHIL KRLAKQDPQL YAKIQLENPL GKKFRNLLCR NCKDLAKAFN
SEKAEEEFKK HFILAKKVAE ELEILLDKIF PEKI
//
