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Database: UniProt
Entry: F8C547_THEGP
LinkDB: F8C547_THEGP
Original site: F8C547_THEGP 
ID   F8C547_THEGP            Unreviewed;       484 AA.
AC   F8C547;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   08-MAY-2019, entry version 37.
DE   SubName: Full=Pyruvate carboxylase {ECO:0000313|EMBL:AEH22814.1};
DE            EC=6.4.1.1 {ECO:0000313|EMBL:AEH22814.1};
GN   OrderedLocusNames=TOPB45_0712 {ECO:0000313|EMBL:AEH22814.1};
OS   Thermodesulfobacterium geofontis (strain OPF15).
OC   Bacteria; Thermodesulfobacteria; Thermodesulfobacteriales;
OC   Thermodesulfobacteriaceae; Thermodesulfobacterium.
OX   NCBI_TaxID=795359 {ECO:0000313|EMBL:AEH22814.1, ECO:0000313|Proteomes:UP000006583};
RN   [1] {ECO:0000313|Proteomes:UP000006583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OPB45 {ECO:0000313|Proteomes:UP000006583};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Davenport K., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I.,
RA   Hamilton-Brehm S., Elkins J., Woyke T.;
RT   "Complete sequence of Thermodesulfobacterium sp. OPB45.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AEH22814.1, ECO:0000313|Proteomes:UP000006583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OPB45 {ECO:0000313|Proteomes:UP000006583};
RX   PubMed=23580711;
RA   Elkins J.G., Hamilton-Brehm S.D., Lucas S., Han J., Lapidus A.,
RA   Cheng J.F., Goodwin L.A., Pitluck S., Peters L., Mikhailova N.,
RA   Davenport K.W., Detter J.C., Han C.S., Tapia R., Land M.L., Hauser L.,
RA   Kyrpides N.C., Ivanova N.N., Pagani I., Bruce D., Woyke T.,
RA   Cottingham R.W.;
RT   "Complete Genome Sequence of the Hyperthermophilic Sulfate-Reducing
RT   Bacterium Thermodesulfobacterium geofontis OPF15T.";
RL   Genome Announc. 1:E00162-13(2013).
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DR   EMBL; CP002829; AEH22814.1; -; Genomic_DNA.
DR   RefSeq; WP_013909514.1; NC_015682.1.
DR   STRING; 795359.TOPB45_0712; -.
DR   EnsemblBacteria; AEH22814; AEH22814; TOPB45_0712.
DR   KEGG; top:TOPB45_0712; -.
DR   PATRIC; fig|795359.3.peg.721; -.
DR   eggNOG; ENOG4105CER; Bacteria.
DR   eggNOG; COG0439; LUCA.
DR   KO; K01961; -.
DR   OMA; YFPRVRH; -.
DR   OrthoDB; 361205at2; -.
DR   BioCyc; TGEO795359:G1GYD-742-MONOMER; -.
DR   Proteomes; UP000006583; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR005481; BC-like_N.
DR   InterPro; IPR011764; Biotin_carboxylation_dom.
DR   InterPro; IPR005482; Biotin_COase_C.
DR   InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   Pfam; PF02785; Biotin_carb_C; 1.
DR   Pfam; PF00289; Biotin_carb_N; 1.
DR   Pfam; PF02786; CPSase_L_D2; 1.
DR   SMART; SM00878; Biotin_carb_C; 1.
DR   SUPFAM; SSF51246; SSF51246; 1.
DR   SUPFAM; SSF52440; SSF52440; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS50979; BC; 1.
DR   PROSITE; PS00866; CPSASE_1; 1.
DR   PROSITE; PS00867; CPSASE_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006583};
KW   Ligase {ECO:0000313|EMBL:AEH22814.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Pyruvate {ECO:0000313|EMBL:AEH22814.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006583}.
FT   DOMAIN        3    450       Biotin carboxylation.
FT                                {ECO:0000259|PROSITE:PS50979}.
FT   DOMAIN      122    321       ATP-grasp. {ECO:0000259|PROSITE:PS50975}.
SQ   SEQUENCE   484 AA;  54473 MW;  3078A02616CB1129 CRC64;
     MRKIKKVLIA NRGVPAVRIM NTCRDKRIKT VAIYSTPDRL SYHVFLADEA VHIGEGPPQE
     SYLNMEKIIK AALERGCDAI HPGWGFLAEN PDFAEMVESA GLIWVGPPAE VIRLMGDKIR
     AKKIAQRANI PTIPALLKVN TVEDILKWME EEEIEFPIMI KAAAGGGGKG MVRVDRKEAL
     PLSLEKAKSE AKKAFGDDTV FVEKYIQGGR HIEVQICGDK YGKIVHLYER ECTIQRRNQK
     ILEEAPSPSI NDDLRQEICF TAIRFMREIG YSSVGTVEFL FDPKTKKFYF LEVNTRLQVE
     HGITELATGL DIVGLMFDIA EGKRLPFSQE DIVPNRHAIE VRINAEDPKN FNPSFGTITR
     LEIPQGPGIR VSSGVYEGAE VPPYYDSLIM LVMSAGADRN EAIRVMDRAL SRGLRVEGIK
     TTAPLLLSII RHPEFIKGNF STRFIEEHYE ELLSMFKEKT PDDEVLKIAQ YIAEISALGP
     QSWM
//
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