ID F8C662_THEGP Unreviewed; 595 AA.
AC F8C662;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:AEH23213.1};
GN OrderedLocusNames=TOPB45_1125 {ECO:0000313|EMBL:AEH23213.1};
OS Thermodesulfobacterium geofontis (strain OPF15).
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae;
OC Thermodesulfobacterium.
OX NCBI_TaxID=795359 {ECO:0000313|EMBL:AEH23213.1, ECO:0000313|Proteomes:UP000006583};
RN [1] {ECO:0000313|EMBL:AEH23213.1, ECO:0000313|Proteomes:UP000006583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OPF15 {ECO:0000313|EMBL:AEH23213.1,
RC ECO:0000313|Proteomes:UP000006583};
RX PubMed=23580711; DOI=10.1128/genomea.00162-13;
RA Elkins J.G., Hamilton-Brehm S.D., Lucas S., Han J., Lapidus A., Cheng J.F.,
RA Goodwin L.A., Pitluck S., Peters L., Mikhailova N., Davenport K.W.,
RA Detter J.C., Han C.S., Tapia R., Land M.L., Hauser L., Kyrpides N.C.,
RA Ivanova N.N., Pagani I., Bruce D., Woyke T., Cottingham R.W.;
RT "Complete genome sequence of the hyperthermophilic sulfate-reducing
RT bacterium Thermodesulfobacterium geofontis OPF15T.";
RL Genome Announc. 1:E0016213-E0016213(2013).
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DR EMBL; CP002829; AEH23213.1; -; Genomic_DNA.
DR RefSeq; WP_013909911.1; NC_015682.1.
DR AlphaFoldDB; F8C662; -.
DR STRING; 795359.TOPB45_1125; -.
DR KEGG; top:TOPB45_1125; -.
DR PATRIC; fig|795359.3.peg.1137; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG3322; Bacteria.
DR HOGENOM; CLU_458499_0_0_0; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000006583; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR007892; CHASE4.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF05228; CHASE4; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006583};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..595
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 595 AA; 69660 MW; 1703EA496181A15C CRC64;
MSLKKFFLLL STFIFSFLLI SYLFIFKFLE SNFLSLEKEN SKNRVNKIEN YFQKEMTKLH
NLTKDWAAWD DAYLFMENKN FKKFIKANLT PSTYLNLKID LLLYTYLNGK IKAGGLFNKK
SGKIYLNREL LNLIKENLKN LSNKNLYDYK KLVLFMDKPF IISIYPVLKS NYTGPPKGYL
FMGRFLTSED INTLANFFDV KDLQIFKSDK PSPEINFIKA DFNEIILEKN HFLNDKNLKV
KVSFFVEKPY IKSIIPFIGI TQISLFLIFA IIMSFLIDKY ILKPLLKLLS EIKEVENKEK
TRLSLDYPTK EYKNLASVIN EFLENISVRE NIYKAVAEKT ENLILLFNGE KNIIFKNANV
DLYFDSEELK YLIEKISEEL KNIELFEGKL EIKNFNIKNY WFNFQIIEVF KNLYLLIGQN
ITEAKLKEEK LFKMATQDFL TGLYNRRYLE DALERIMAAS KRGEKFVLLF IDCDDLKKIN
DTYGHLIGDK VLKVVAQAIK DSIRKEDLGC RWGGDEFVVI LNHCDKNLGI KIAERIINKL
ENSEIKLNSV KIKPSVSIGI VEIDGTKEIK EVLDLADKFA YRAKLNGKPK IIYEI
//
