ID F8DYZ9_CORRG Unreviewed; 507 AA.
AC F8DYZ9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=C4-dicarboxylate transport protein {ECO:0000313|EMBL:AEI09744.1};
GN Name=dctA {ECO:0000313|EMBL:AEI09744.1};
GN OrderedLocusNames=CRES_1389 {ECO:0000313|EMBL:AEI09744.1};
OS Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026 / SICGH
OS 158).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=662755 {ECO:0000313|EMBL:AEI09744.1, ECO:0000313|Proteomes:UP000000492};
RN [1] {ECO:0000313|EMBL:AEI09744.1, ECO:0000313|Proteomes:UP000000492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45100 / JCM 12819 / GTC 2026 / SICGH 158
RC {ECO:0000313|Proteomes:UP000000492};
RX PubMed=22524407; DOI=10.1186/1471-2164-13-141;
RA Schroder J., Maus I., Meyer K., Wordemann S., Blom J., Jaenicke S.,
RA Schneider J., Trost E., Tauch A.;
RT "Complete genome sequence, lifestyle, and multi-drug resistance of the
RT human pathogen Corynebacterium resistens DSM 45100 isolated from blood
RT samples of a leukemia patient.";
RL BMC Genomics 13:141-141(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002857; AEI09744.1; -; Genomic_DNA.
DR AlphaFoldDB; F8DYZ9; -.
DR STRING; 662755.CRES_1389; -.
DR KEGG; crd:CRES_1389; -.
DR eggNOG; COG1301; Bacteria.
DR HOGENOM; CLU_019375_7_0_11; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000000492; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000492};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 453..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 53190 MW; AD1A312DCE783D49 CRC64;
MAYTEINSDR GPSIAPSKRE KKDNTHWLYI AVIIAVIGGI VLGLVAPDTA KALKPLGSTF
VDIIKMIIPP VIFCTIVLGI GSVRAAASVG KAGGIALAYF ITMSTFALAI GLAVGNIIQP
GEGLDIHANA KAVQDALDKN AEQPHGLMGF IQSIVPDTFF SAFTSGSVLQ VLVIALLVGF
AIQSMGKAGE PILGFVAHLQ KLVFKILGWI LWLAPIGAFG AIAAVVGATG VKAVVQLGVL
MLAFYLTCLI FIFVILGTIL KVFTGFNIFK LVKYLGKEFL LIFATSSSES ALPNLMRKME
HIGVDKSTVG IVVPTGYSFN LDGTAIYLTM ASIFVADAMG KPMSVGEQIS LLVFMIIASK
GAAGVTGAGI ATLAAGLQSH RPDLLDGVGV IVGIDRFMSE ARALTNFAGN SVATLLVGTW
TKTIDKEQVH RVLDGKDPYV ATEEDGDVNL RYPSVSNPAT ENLQPTPQLN LDAYHGSAAS
TSGEAQPASQ SGDERPDLST SKGPLDK
//
