ID F8E076_CORRG Unreviewed; 457 AA.
AC F8E076;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative phosphate starvation-inducible protein {ECO:0000313|EMBL:AEI09947.1};
GN Name=phoH1 {ECO:0000313|EMBL:AEI09947.1};
GN OrderedLocusNames=CRES_1594 {ECO:0000313|EMBL:AEI09947.1};
OS Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026 / SICGH
OS 158).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=662755 {ECO:0000313|EMBL:AEI09947.1, ECO:0000313|Proteomes:UP000000492};
RN [1] {ECO:0000313|EMBL:AEI09947.1, ECO:0000313|Proteomes:UP000000492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45100 / JCM 12819 / GTC 2026 / SICGH 158
RC {ECO:0000313|Proteomes:UP000000492};
RX PubMed=22524407; DOI=10.1186/1471-2164-13-141;
RA Schroder J., Maus I., Meyer K., Wordemann S., Blom J., Jaenicke S.,
RA Schneider J., Trost E., Tauch A.;
RT "Complete genome sequence, lifestyle, and multi-drug resistance of the
RT human pathogen Corynebacterium resistens DSM 45100 isolated from blood
RT samples of a leukemia patient.";
RL BMC Genomics 13:141-141(2012).
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
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DR EMBL; CP002857; AEI09947.1; -; Genomic_DNA.
DR RefSeq; WP_013888935.1; NC_015673.1.
DR AlphaFoldDB; F8E076; -.
DR STRING; 662755.CRES_1594; -.
DR KEGG; crd:CRES_1594; -.
DR eggNOG; COG1875; Bacteria.
DR HOGENOM; CLU_022283_2_1_11; -.
DR OrthoDB; 9766527at2; -.
DR Proteomes; UP000000492; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000000492};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 25..152
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
SQ SEQUENCE 457 AA; 49424 MW; D856851EE5764843 CRC64;
MTLPANTTVR TPVASASQAA EQGVKTYVLD TSVLLSDPWA LLKFAEHRII LPVVVISELE
GKRHHPELGW FARQTLGLLE DFRHSTGRLD VPTTVNDEGG TVHVELNHID QSILPSGLRG
EENDHRILAC ALNLRAEGHD VTLVTKDVPL RVKAGAVGLA ADEYHAQDVV LTGYKGMARA
EVPSHLIDEV YETGETELTG ALTVDGDEVD ELPIHCGLQL TAGSQSALAR TTGDGWARQV
PADLEAFGIR GRSAQQRIAL DLLLDEEIGI VSLGGSAGTG KSALALCAGL EAVMERGTHR
KIVVFRPLYA VGGQDLGYLP GSESDKMNPW AQAVYDTLEG VVSENVLEEI DARGMLEVLP
LTHIRGRSLN DSFVIVDEAQ SLERNVLLTV LSRLGRNSRV VLTHDVAQRD NLRVGRHDGI
QAVIEKLKGN PLFAHITLTR SERSRVAELV TGLLENG
//
