ID F8J5V2_HYPSM Unreviewed; 311 AA.
AC F8J5V2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator) {ECO:0000313|EMBL:CCB63391.1};
GN Name=cysB {ECO:0000313|EMBL:CCB63391.1};
GN OrderedLocusNames=HYPMC_0150 {ECO:0000313|EMBL:CCB63391.1};
OS Hyphomicrobium sp. (strain MC1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=717785 {ECO:0000313|EMBL:CCB63391.1, ECO:0000313|Proteomes:UP000000494};
RN [1] {ECO:0000313|Proteomes:UP000000494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC1 {ECO:0000313|Proteomes:UP000000494};
RA Genoscope.;
RT "The complete genome of Hyphomicrobium sp. MC1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; FQ859181; CCB63391.1; -; Genomic_DNA.
DR RefSeq; WP_013945804.1; NC_015717.1.
DR AlphaFoldDB; F8J5V2; -.
DR STRING; 717785.HYPMC_0150; -.
DR KEGG; hmc:HYPMC_0150; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_2_5; -.
DR Proteomes; UP000000494; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08413; PBP2_CysB_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037423; CysB_PBP2.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF6; HTH-TYPE TRANSCRIPTIONAL REGULATOR CYSB-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000494};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 311 AA; 34795 MW; 8F0C5CA0A541E521 CRC64;
MNFQQLRIIR ETVRHRFNLT EAANILFTSQ SGVSKHIRDL EQELGVEIFV RHGKRLLGLT
DPGKEVVKIV ERILVDAENL SRVVADFSDG DEGILRVATT HTQARYTLPA VIARFKETFP
DVRLNLQQAN PKDLPTILRE GDADIAIATD TLDDHPGIIA FPYHTWDHAV VVPRGHALAK
EKTLTLAAIA AWPIITYDDG LTGRRRIDQA FEAAGLTPDI SITALDADVI KAYAELGMGV
GIIASVAYDR EHDRKLVRID APNLFLPSTS SIAVRRGRLL RRYAYRFIEH CNPRLTEQAI
RIADSDQPQD L
//
