ID F8K0M7_STREN Unreviewed; 343 AA.
AC F8K0M7; G8X2D2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Type III PKS {ECO:0000313|EMBL:AEW94567.1};
GN OrderedLocusNames=SCATT_21960 {ECO:0000313|EMBL:AEW94567.1};
OS Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925
OS / NBRC 14057 / NRRL 8057) (Streptomyces cattleya).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptantibioticus.
OX NCBI_TaxID=1003195 {ECO:0000313|EMBL:AEW94567.1, ECO:0000313|Proteomes:UP000007842};
RN [1] {ECO:0000313|Proteomes:UP000007842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057
RC {ECO:0000313|Proteomes:UP000007842};
RA Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.;
RT "Complete genome sequence of Streptomyces cattleya strain DSM 46488.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003219; AEW94567.1; -; Genomic_DNA.
DR RefSeq; WP_014142962.1; NC_017586.1.
DR AlphaFoldDB; F8K0M7; -.
DR STRING; 1003195.SCATT_21960; -.
DR KEGG; scy:SCATT_21960; -.
DR PATRIC; fig|1003195.11.peg.3729; -.
DR eggNOG; COG3424; Bacteria.
DR HOGENOM; CLU_034992_0_0_11; -.
DR OrthoDB; 4334218at2; -.
DR Proteomes; UP000007842; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007842}.
FT DOMAIN 64..201
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 215..337
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 138
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 343 AA; 36544 MW; A4465FC1D5B5F947 CRC64;
MHAHVTPPTV RLADHAITID DLRNDHRTHL PDHPKLLALL RYLGQTGVET LYWSRPIEEA
AAPVGVEART QAANADARRM AAEAATEAIA SAGLSPGDID AVITSHTVWA LPTLDVTLVG
DVGLRPDVAR IPMATVACAG GVQGLVRATD LVRARPGTRV LVVVSEVLST SYHRSETTPQ
HAIYKALFSD SAAACVVSAD PLAPGFAIEE TWEWVMPDSD DRYWGRLDAA GFHFESTKMA
PAAPRDSMPD LVKWLDGWRP SWVVIHPGGP GIIEDVARAL DLDPAVAARH AYASLTENGN
LGGAGVLDVL RRTHSTPPPA GADGLMVGFG PGFTVTALRG TWR
//
