ID   F8KRH6_HELBC            Unreviewed;       352 AA.
AC   F8KRH6;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase {ECO:0000313|EMBL:CCB79361.1};
DE            EC=2.1.1.61 {ECO:0000313|EMBL:CCB79361.1};
GN   OrderedLocusNames=HBZC1_03750 {ECO:0000313|EMBL:CCB79361.1};
OS   Helicobacter bizzozeronii (strain CIII-1).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1002804 {ECO:0000313|EMBL:CCB79361.1, ECO:0000313|Proteomes:UP000008387};
RN   [1] {ECO:0000313|EMBL:CCB79361.1, ECO:0000313|Proteomes:UP000008387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIII-1 {ECO:0000313|EMBL:CCB79361.1,
RC   ECO:0000313|Proteomes:UP000008387};
RX   PubMed=21705603; DOI=10.1128/JB.05439-11;
RA   Schott T., Rossi M., Hanninen M.L.;
RT   "Genome sequence of Helicobacter bizzozeronii strain CIII-1, an isolate
RT   from human gastric mucosa.";
RL   J. Bacteriol. 193:4565-4566(2011).
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DR   EMBL; FR871757; CCB79361.1; -; Genomic_DNA.
DR   RefSeq; WP_013889852.1; NC_015674.1.
DR   AlphaFoldDB; F8KRH6; -.
DR   STRING; 1002804.HBZC1_03750; -.
DR   KEGG; hbi:HBZC1_03750; -.
DR   eggNOG; COG0482; Bacteria.
DR   HOGENOM; CLU_053822_0_0_7; -.
DR   Proteomes; UP000008387; Chromosome.
DR   GO; GO:0004808; F:tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11933:SF6; THIL AANH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11933; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE; 1.
DR   Pfam; PF18297; NFACT-R_2; 1.
DR   Pfam; PF03054; tRNA_Me_trans; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:CCB79361.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008387};
KW   Transferase {ECO:0000313|EMBL:CCB79361.1}.
SQ   SEQUENCE   352 AA;  39479 MW;  4869701A16C0E964 CRC64;
     MKALALFSGG LDSLLSMYLV ASQGVEVSAL HFNIGFGGNK DKLEYLQNAT QQIGVGLLVC
     DIQEQFFNEV LFEPKYGYGK YFNPCIDCHA NMFRQAFYKL LELKADFVIS GEVLGQRPKS
     QRKEALGQVR KLVRGFGAEA CFDSILDRSG KDPSKPQFLD ELLLRPMSAQ LLEPSFMEKQ
     GWVDRAKLWD IQGRSRVRQL AKVQELGLKY YEKPGGGCLL TDLSVSAKLK DLQAHRQNTQ
     QQMVVQDNLI VKVGRYMVVG NTRVIVGRNE LENAKLQAPH PLMDKIELLD CKGPLGLVEK
     CASLEEKKLA AQIVLSYAKS EKERAYGVQV GAEVLHLNPL QKEEAQKYLF MG
//