ID   F8KS40_HELBC            Unreviewed;       357 AA.
AC   F8KS40;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:CCB79590.1};
DE            EC=3.5.1.28 {ECO:0000313|EMBL:CCB79590.1};
GN   OrderedLocusNames=HBZC1_06040 {ECO:0000313|EMBL:CCB79590.1};
OS   Helicobacter bizzozeronii (strain CIII-1).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1002804 {ECO:0000313|EMBL:CCB79590.1, ECO:0000313|Proteomes:UP000008387};
RN   [1] {ECO:0000313|EMBL:CCB79590.1, ECO:0000313|Proteomes:UP000008387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIII-1 {ECO:0000313|EMBL:CCB79590.1,
RC   ECO:0000313|Proteomes:UP000008387};
RX   PubMed=21705603; DOI=10.1128/JB.05439-11;
RA   Schott T., Rossi M., Hanninen M.L.;
RT   "Genome sequence of Helicobacter bizzozeronii strain CIII-1, an isolate
RT   from human gastric mucosa.";
RL   J. Bacteriol. 193:4565-4566(2011).
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DR   EMBL; FR871757; CCB79590.1; -; Genomic_DNA.
DR   RefSeq; WP_013890061.1; NC_015674.1.
DR   AlphaFoldDB; F8KS40; -.
DR   STRING; 1002804.HBZC1_06040; -.
DR   KEGG; hbi:HBZC1_06040; -.
DR   eggNOG; COG0860; Bacteria.
DR   HOGENOM; CLU_014322_11_1_7; -.
DR   Proteomes; UP000008387; Chromosome.
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR   CDD; cd02696; MurNAc-LAA; 1.
DR   Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR002508; MurNAc-LAA_cat.
DR   PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR   PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR   Pfam; PF01520; Amidase_3; 1.
DR   SMART; SM00646; Ami_3; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:CCB79590.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008387};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..357
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003379068"
FT   DOMAIN          195..350
FT                   /note="MurNAc-LAA"
FT                   /evidence="ECO:0000259|SMART:SM00646"
SQ   SEQUENCE   357 AA;  40336 MW;  DD27BEB177F1FFB4 CRC64;
     MRFIWLCLVL CLGLSAHALK ITQIVPFGTS SVRISFNKDF HPSAFKTIHL SPSKDLVEIK
     AQLLVPSKIY PFSHNTSIKI SKHGKHLAKV FIKFHKHTPY QLKITNNHLY ISLSNAPPTP
     SPPPPPPEPA PKRFKIVLDP GHGGRDCGAM GVSHVCEKHI VLHVAKYLQK ELKERGYIVY
     MTRHNDHYIG LKERTEFANN KEADLFISIH ANSIPKHSTS NPKGVETYFL SPARSERARK
     VAEQENQDDV RGMDYFSKMS FLNSLNSQRL VISNKLAIDI QFGILSLLRQ HYQGVIDGGV
     REGPFWVLAG ALMPSVLIEI GYNSNPKESK RLQDKTYQQF LAKGIANGIQ SFFEKNY
//