ID F8KUE3_HELBC Unreviewed; 422 AA.
AC F8KUE3;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=UDP-glucose dehydrogenase {ECO:0000313|EMBL:CCB80503.1};
DE EC=1.1.1.22 {ECO:0000313|EMBL:CCB80503.1};
GN OrderedLocusNames=HBZC1_15170 {ECO:0000313|EMBL:CCB80503.1};
OS Helicobacter bizzozeronii (strain CIII-1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1002804 {ECO:0000313|EMBL:CCB80503.1, ECO:0000313|Proteomes:UP000008387};
RN [1] {ECO:0000313|EMBL:CCB80503.1, ECO:0000313|Proteomes:UP000008387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIII-1 {ECO:0000313|EMBL:CCB80503.1,
RC ECO:0000313|Proteomes:UP000008387};
RX PubMed=21705603; DOI=10.1128/JB.05439-11;
RA Schott T., Rossi M., Hanninen M.L.;
RT "Genome sequence of Helicobacter bizzozeronii strain CIII-1, an isolate
RT from human gastric mucosa.";
RL J. Bacteriol. 193:4565-4566(2011).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; FR871757; CCB80503.1; -; Genomic_DNA.
DR RefSeq; WP_013890903.1; NC_015674.1.
DR AlphaFoldDB; F8KUE3; -.
DR STRING; 1002804.HBZC1_15170; -.
DR KEGG; hbi:HBZC1_15170; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_1_7; -.
DR Proteomes; UP000008387; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CCB80503.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008387}.
FT DOMAIN 315..413
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 422 AA; 47040 MW; 95C07AFECA4EBE60 CRC64;
MFKENPTLGI LGLGFVGLPL ALAFGQHFKT IGFDISSQRI AELQNGHDRN QQASQPDFLK
ARLLQITSCP QDLSGVDVFI IAVPTPVDLH NQPDLNMLKN ASLLAGSHLQ QQGIVIYEST
TYPTCTQEFC VPLLEQASHL RYNHDFFVGY SPERINVGDA RPLSQIVKIT SGSTPESARY
IDQLYQRVIC QTHLVSSIEV AESAKILENT QRDLNIAFIN DMAMLLDRLG VNLYEVLEAC
QTKWNFVPFI PGLVGGHCIS IDPYYLSFLA RRVQHDPSLI EASRQINNAM PAFLANKIAK
LLHTHQLSIQ KARVLILGAS FKENCNDLRN SQSLVLKQEL ESLGCGVDIY DPLIGFEDMQ
ALFASTALQT LPQEPTYHAV ILVVAHRCFA DLDLSGVLLD QGFIYDLKAF LKRQPCLDIY
TP
//
