ID F8KWC8_PARAV Unreviewed; 722 AA.
AC F8KWC8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Transcription elongation factor greA {ECO:0000313|EMBL:CCB85326.1};
GN Name=greA {ECO:0000313|EMBL:CCB85326.1};
GN OrderedLocusNames=PUV_03760 {ECO:0000313|EMBL:CCB85326.1};
OS Parachlamydia acanthamoebae (strain UV7).
OC Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Parachlamydiaceae;
OC Parachlamydia.
OX NCBI_TaxID=765952 {ECO:0000313|EMBL:CCB85326.1, ECO:0000313|Proteomes:UP000000495};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UV7;
RA Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA Myers G.S.A., Horn M.;
RT "Unity in variety -- the pan-genome of the Chlamydiae.";
RL Mol. Biol. Evol. 0:0-0(2011).
RN [2] {ECO:0000313|EMBL:CCB85326.1, ECO:0000313|Proteomes:UP000000495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UV7 {ECO:0000313|Proteomes:UP000000495};
RX PubMed=21690563; DOI=10.1093/molbev/msr161;
RA Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA Myers G.S., Horn M.;
RT "Unity in variety--the pan-genome of the Chlamydiae.";
RL Mol. Biol. Evol. 28:3253-3270(2011).
CC -!- SIMILARITY: Belongs to the GreA/GreB family.
CC {ECO:0000256|ARBA:ARBA00008213}.
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DR EMBL; FR872580; CCB85326.1; -; Genomic_DNA.
DR AlphaFoldDB; F8KWC8; -.
DR STRING; 765952.PUV_03760; -.
DR KEGG; puv:PUV_03760; -.
DR eggNOG; COG0782; Bacteria.
DR eggNOG; COG1747; Bacteria.
DR HOGENOM; CLU_026840_1_0_0; -.
DR Proteomes; UP000000495; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR Gene3D; 3.10.50.30; Transcription elongation factor, GreA/GreB, C-terminal domain; 1.
DR Gene3D; 1.10.287.180; Transcription elongation factor, GreA/GreB, N-terminal domain; 1.
DR InterPro; IPR036953; GreA/GreB_C_sf.
DR InterPro; IPR018151; TF_GreA/GreB_CS.
DR InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N.
DR InterPro; IPR036805; Tscrpt_elong_fac_GreA/B_N_sf.
DR PANTHER; PTHR30437; TRANSCRIPTION ELONGATION FACTOR GREA; 1.
DR PANTHER; PTHR30437:SF4; TRANSCRIPTION ELONGATION FACTOR GREA; 1.
DR Pfam; PF01272; GreA_GreB; 1.
DR Pfam; PF03449; GreA_GreB_N; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF46557; GreA transcript cleavage protein, N-terminal domain; 1.
DR PROSITE; PS00830; GREAB_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Elongation factor {ECO:0000313|EMBL:CCB85326.1};
KW Protein biosynthesis {ECO:0000313|EMBL:CCB85326.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000495};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 571..641
FT /note="Transcription elongation factor GreA/GreB N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF03449"
FT DOMAIN 650..710
FT /note="Transcription elongation factor GreA/GreB C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01272"
FT COILED 615..642
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 722 AA; 83720 MW; FD34EFE807312D9A CRC64;
MGYLEEFHTQ IQNRDFNKFF QLWEEYCTCD VVDVEELLQL LSMIKKSDLA KPFGEYVESA
LPTWEKIENP KDSYEVLKLL IDLETTNTPL LAEITHDILK KHHGNDPLFE ERMRLIGLRK
KDKFQGAIAN YDLLAHMKKG KVVFHNAGWG TGEIMDVSLV REQVILEFEW VSGRKDLSFA
NAFKTLIPLP DDHFLARRFA NPDELEKEAK DDPVAVVQLL LKDLGPKTAA EVKDELCELV
IPEKDWNKWW QGARAKVKKD TMIESPEGIK EPFRLRKTAL KHEDRWQNAI DNQTDTNDLL
QTSYQFVRDF PNILKDQEVK KTLQAKITGL LTKSDLLPEQ EVQAHLFLDS FLGLSEHGRM
AQALIVQSDQ PFELIQKVDI TPFKKRALMV VRHSRADWSH IFLEMFAKTD QSTLREYLIK
EICADEEAKT LLLNMLEDLL HYPEKNPELF VWYFQKVVKK ADGIPYNDKE GQGRFLDGFL
VLMHKLEGDP QQRELIRKMY NLISEKRYAV IRALIDGMSK EFVKEFLLLA SKCQTFTEHD
LKILASLATV VHPTLGAARQ SKDTKNDQNT IWTTEEGYLQ TQERIRQIGT TEVVENAREI
EAARSLGDLR ENSEYKFALE KRSRLQGELK RLSEQLNRAR IITKDDIYLN QVSVGSIVEL
EDPEKNVVTY TILGPWDADA DTNILSFQSK FAEAMLGRKV GEEFEFRNQN FTIRTIKNIF
QD
//
