ID F8PME4_SERL3 Unreviewed; 628 AA.
AC F8PME4;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 28-JUN-2023, entry version 39.
DE RecName: Full=Vacuolar protein 8 {ECO:0000256|ARBA:ARBA00026209};
GN ORFNames=SERLA73DRAFT_102750 {ECO:0000313|EMBL:EGO02776.1};
OS Serpula lacrymans var. lacrymans (strain S7.3) (Dry rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Coniophorineae; Serpulaceae; Serpula.
OX NCBI_TaxID=936435 {ECO:0000313|Proteomes:UP000008063};
RN [1] {ECO:0000313|Proteomes:UP000008063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain S7.3 {ECO:0000313|Proteomes:UP000008063};
RX PubMed=21764756; DOI=10.1126/science.1205411;
RA Eastwood D.C., Floudas D., Binder M., Majcherczyk A., Schneider P.,
RA Aerts A., Asiegbu F.O., Baker S.E., Barry K., Bendiksby M., Blumentritt M.,
RA Coutinho P.M., Cullen D., de Vries R.P., Gathman A., Goodell B.,
RA Henrissat B., Ihrmark K., Kauserud H., Kohler A., LaButti K., Lapidus A.,
RA Lavin J.L., Lee Y.-H., Lindquist E., Lilly W., Lucas S., Morin E.,
RA Murat C., Oguiza J.A., Park J., Pisabarro A.G., Riley R., Rosling A.,
RA Salamov A., Schmidt O., Schmutz J., Skrede I., Stenlid J., Wiebenga A.,
RA Xie X., Kuees U., Hibbett D.S., Hoffmeister D., Hoegberg N., Martin F.,
RA Grigoriev I.V., Watkinson S.C.;
RT "The plant cell wall-decomposing machinery underlies the functional
RT diversity of forest fungi.";
RL Science 333:762-765(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004635}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004592}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004592}.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; GL945476; EGO02776.1; -; Genomic_DNA.
DR AlphaFoldDB; F8PME4; -.
DR STRING; 936435.F8PME4; -.
DR eggNOG; KOG4224; Eukaryota.
DR HOGENOM; CLU_021483_0_0_1; -.
DR InParanoid; F8PME4; -.
DR OMA; VWDKPDG; -.
DR OrthoDB; 2721872at2759; -.
DR Proteomes; UP000008063; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR GO; GO:0071562; P:nucleus-vacuole junction assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045156; Vac8.
DR PANTHER; PTHR47249; VACUOLAR PROTEIN 8; 1.
DR PANTHER; PTHR47249:SF1; VACUOLAR PROTEIN 8; 1.
DR Pfam; PF00514; Arm; 6.
DR SMART; SM00185; ARM; 9.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 7.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000008063};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT REPEAT 89..124
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 136..178
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 177..219
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 218..258
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 261..303
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 302..344
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 343..386
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 530..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..621
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 68043 MW; 6A8C1EBB40F0BA1C CRC64;
MGVVSSCCDS CFHSRRSQQY EPLLLENERE AVADLLQFLE NRTNTNFFTG DPLSALTTLS
FSDNVDLQRS AALAFAEITE KEVRPVGRDT LDPILFLLSS HDTEVQRAAS AALGNLAVNS
ASDREPDNKL LIVKLGGLEP LIRQMLSPNV EVQCNAVGCV TNLATHDDNK TKIARSGALV
PLTRLARSKD MRVQRNATGA LLNMTHSDEN RQQLVNAGAI PVLVSLLNSM DTDVQYYCTT
ALSNIAVDGT NRKKLAQSEP KLVTSLVALM DSPSLKVQCQ AALALRNLAS DEKYQLEIVK
ADGLTSLLRL LQSTYLPLIL SSAACVRNVS IHPQNESPII ESGFLQPLIN LLSFKDNEEV
QCHAISTLRN LAASSEKNKT AIVKAGAIQS IKELVLEVPM NVQSEMTACV AVLALSDELK
GQLLEMGICE ALIPLTNSPS SEVQGNSAAA LGNLSSKDGR TASDDYSAFN DVWDKPDGGM
HRYLYRFLSS TDATFQHIAV WTIVQLLESG DPQLISNIRS STLLNPSIRQ LASSRTPTPT
SSVGTPRSHH SQHSYQDTDT GEGQGEIQLL ARRILDFVDG EGDGAIPRSV SGSHMQPGSS
LDESSSGREH EELRRSVREA FGSSSHGH
//
