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Database: UniProt
Entry: F9CW12_9ARCH
LinkDB: F9CW12_9ARCH
Original site: F9CW12_9ARCH 
ID   F9CW12_9ARCH            Unreviewed;       336 AA.
AC   F9CW12;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   08-MAY-2019, entry version 32.
DE   SubName: Full=Homoserine dehydrogenase {ECO:0000313|EMBL:EGP93464.1};
GN   ORFNames=MY1_0701 {ECO:0000313|EMBL:EGP93464.1};
OS   Nitrosarchaeum koreense MY1.
OC   Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae;
OC   Nitrosarchaeum.
OX   NCBI_TaxID=1001994 {ECO:0000313|EMBL:EGP93464.1, ECO:0000313|Proteomes:UP000004440};
RN   [1] {ECO:0000313|EMBL:EGP93464.1, ECO:0000313|Proteomes:UP000004440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MY1 {ECO:0000313|EMBL:EGP93464.1,
RC   ECO:0000313|Proteomes:UP000004440};
RX   PubMed=21914867; DOI=10.1128/JB.05717-11;
RA   Kim B.K., Jung M.Y., Yu D.S., Park S.J., Oh T.K., Rhee S.K., Kim J.F.;
RT   "Genome Sequence of an Ammonia-Oxidizing Soil Archaeon, "Candidatus
RT   Nitrosoarchaeum koreensis" MY1.";
RL   J. Bacteriol. 193:5539-5540(2011).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGP93464.1}.
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DR   EMBL; AFPU01000001; EGP93464.1; -; Genomic_DNA.
DR   RefSeq; WP_007550224.1; NZ_AFPU01000001.1.
DR   EnsemblBacteria; EGP93464; EGP93464; MY1_0701.
DR   PATRIC; fig|1001994.6.peg.684; -.
DR   eggNOG; arCOG01351; Archaea.
DR   eggNOG; COG0460; LUCA.
DR   OrthoDB; 102435at2157; -.
DR   Proteomes; UP000004440; Unassembled WGS sequence.
DR   GO; GO:0004412; F:homoserine dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR   InterPro; IPR001342; HDH_cat.
DR   InterPro; IPR022697; HDH_short.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00742; Homoserine_dh; 1.
DR   Pfam; PF03447; NAD_binding_3; 1.
DR   PIRSF; PIRSF036497; HDH_short; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000004440};
KW   NADP {ECO:0000256|PIRSR:PIRSR036497-2}.
FT   DOMAIN        7    141       NAD_binding_3. {ECO:0000259|Pfam:
FT                                PF03447}.
FT   DOMAIN      156    327       Homoserine_dh. {ECO:0000259|Pfam:
FT                                PF00742}.
FT   NP_BIND       7     12       NADP. {ECO:0000256|PIRSR:PIRSR036497-2}.
FT   ACT_SITE    223    223       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR036497-1}.
FT   BINDING     124    124       NADP. {ECO:0000256|PIRSR:PIRSR036497-2}.
FT   BINDING     208    208       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR036497-2}.
SQ   SEQUENCE   336 AA;  36282 MW;  A6C9DDA6ABCF78C9 CRC64;
     MRIILCGFGV VGQSLVKLFD SRSEDLYAEY GLKPRVVGVF DSKGSAVDIS GLELEKLIEV
     KKKTGTVKNY ANTKNNMSGI DMIKNLDADV VIETTASNYK DAEPGMTHIV TAMKRGMHVI
     SVNKGPLALA FPSLMELAIY NQVIFKFSGT VGGGTPILDY AKNSLRGERI SSFSGILNGT
     TNYILTNMAN GLSFETALKD AKDKGYVEAD ESLDLDGLDA AAKLVILANW VMDMKVTMPD
     ISCKGIRNVT EEDIKKARKN NCAIKLIASC NKELIVEPKE VSVDDPLCVN GTLNAIAFTS
     EHSGTQTIIG KGAGGMETAS SILRDLLDIR QEIVKI
//
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