ID F9D249_PREDD Unreviewed; 721 AA.
AC F9D249;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Alpha-1,2-mannosidase {ECO:0000313|EMBL:AGB28390.1, ECO:0000313|EMBL:EGQ15867.1};
DE EC=3.2.1.113 {ECO:0000313|EMBL:EGQ15867.1};
GN OrderedLocusNames=Prede_1054 {ECO:0000313|EMBL:AGB28390.1};
GN ORFNames=HMPREF9136_0927 {ECO:0000313|EMBL:EGQ15867.1};
OS Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS / ES 2772) (Mitsuokella dentalis).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=908937 {ECO:0000313|EMBL:EGQ15867.1, ECO:0000313|Proteomes:UP000007820};
RN [1] {ECO:0000313|EMBL:EGQ15867.1, ECO:0000313|Proteomes:UP000007820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:EGQ15867.1,
RC ECO:0000313|Proteomes:UP000007820};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGB28390.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:AGB28390.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000010862}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC {ECO:0000313|Proteomes:UP000010862};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR EMBL; CP003368; AGB28390.1; -; Genomic_DNA.
DR EMBL; AFPW01000012; EGQ15867.1; -; Genomic_DNA.
DR RefSeq; WP_005844803.1; NZ_GL982488.1.
DR AlphaFoldDB; F9D249; -.
DR STRING; 908937.Prede_1054; -.
DR KEGG; pdt:Prede_1054; -.
DR PATRIC; fig|908937.9.peg.1104; -.
DR eggNOG; COG3537; Bacteria.
DR HOGENOM; CLU_003690_2_2_10; -.
DR OrthoDB; 9762711at2; -.
DR Proteomes; UP000007820; Unassembled WGS sequence.
DR Proteomes; UP000010862; Chromosome 1.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR005887; GH92_a_mannosidase_put.
DR InterPro; IPR041371; GH92_N.
DR InterPro; IPR012939; Glyco_hydro_92.
DR NCBIfam; TIGR01180; aman2_put; 1.
DR PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF07971; Glyco_hydro_92; 1.
DR Pfam; PF17678; Glyco_hydro_92N; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Glycosidase {ECO:0000313|EMBL:EGQ15867.1};
KW Hydrolase {ECO:0000313|EMBL:EGQ15867.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..721
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007914215"
FT DOMAIN 33..216
FT /note="Glycosyl hydrolase family 92 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17678"
FT DOMAIN 246..708
FT /note="Glycosyl hydrolase family 92"
FT /evidence="ECO:0000259|Pfam:PF07971"
SQ SEQUENCE 721 AA; 80290 MW; 046E2EB2A62E24BD CRC64;
MKRPRLLLLV IATLCLAALP ASAGEQTDGP ARYVNPWIGT GGHGHVFLGA NVPFGFVQLG
PTQTHSGWDW CSGYHYSGRM LRGFSHLHLS GTGIGDLGDV TFLPVADEEQ DSTAFSHDDE
TVRPGYYAIR LQKPEVKVEL TATARAGFHR YTYAPGAKRL MKIDLRHGIG WDALSSSSLR
QVDGRTIEGC RLSTGWAKNQ QVYFTAVFSS AVKLLSCNDN IYTIQVEDDG KPLLVKLGLS
AVGTANAKEN LEHEIPEWNF GAVAREATRL WNQELGKISI KTRNEALRRT FYTALYHTMV
APSVFCDVNG DYRGADGKTH QGNFTNYTTF SLWDTYRAAM PLMTLIHPGM MNDVGETFLH
IYHEQGKLPV WHLVGNETDC MIGNPGIIVL ADLVLKGFVS DKEAAFQAMK ASALKDERGL
GALKQYGYVP FDKDEERETV AKTLEYAIAD AGIAKVARLL GHEEDYKYFL DRSQSYKKLF
DPRDGFMKGR DSEGRFRTPF NPFHAVHRQD DYTEGNAWQY TWLVPHNVHG LVGLFKNEKA
FTQKLDSLFL AQGTLGEDAS PDISGLIGQY AHGNEPSHHI IYMYNYVGQP WKAARLLRQT
LATMYHDDAD GLSGNEDVGQ MSAWYILSAL GLYQVDPADG VFVFGSPLVD EAELQVGGGK
TFRIVSHNNN ERNMYIQQVR LNGKPYPKSY IGYKDIFHGG TLEFTMGSKP SKFGTSVKNR
P
//
