ID F9D6D2_PREDD Unreviewed; 858 AA.
AC F9D6D2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Zinc-dependent metalloprotease {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=Prede_2222 {ECO:0000313|EMBL:AGB29495.1};
GN ORFNames=HMPREF9136_2410 {ECO:0000313|EMBL:EGQ12293.1};
OS Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS / ES 2772) (Mitsuokella dentalis).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=908937 {ECO:0000313|EMBL:EGQ12293.1, ECO:0000313|Proteomes:UP000007820};
RN [1] {ECO:0000313|EMBL:EGQ12293.1, ECO:0000313|Proteomes:UP000007820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:EGQ12293.1,
RC ECO:0000313|Proteomes:UP000007820};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGB29495.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:AGB29495.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 2 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000010862}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC {ECO:0000313|Proteomes:UP000010862};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 2 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003369; AGB29495.1; -; Genomic_DNA.
DR EMBL; AFPW01000042; EGQ12293.1; -; Genomic_DNA.
DR RefSeq; WP_005847406.1; NZ_GL982489.1.
DR AlphaFoldDB; F9D6D2; -.
DR STRING; 908937.Prede_2222; -.
DR KEGG; pdt:Prede_2222; -.
DR PATRIC; fig|908937.9.peg.2357; -.
DR eggNOG; COG5549; Bacteria.
DR HOGENOM; CLU_008630_1_0_10; -.
DR OrthoDB; 9776599at2; -.
DR Proteomes; UP000007820; Unassembled WGS sequence.
DR Proteomes; UP000010862; Chromosome 2.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd04276; ZnMc_MMP_like_2; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR033413; DUF5117.
DR InterPro; IPR033428; DUF5118.
DR InterPro; IPR032534; EcxA_zinc-bd.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR034032; Zn_MMP-like_bac.
DR PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR Pfam; PF16313; DUF4953; 1.
DR Pfam; PF17148; DUF5117; 1.
DR Pfam; PF17162; DUF5118; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..858
FT /note="Zinc-dependent metalloprotease"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010496751"
FT DOMAIN 44..93
FT /note="DUF5118"
FT /evidence="ECO:0000259|Pfam:PF17162"
FT DOMAIN 102..293
FT /note="DUF5117"
FT /evidence="ECO:0000259|Pfam:PF17148"
FT DOMAIN 427..732
FT /note="EcxA zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF16313"
SQ SEQUENCE 858 AA; 95781 MW; B091BC56BCFD5C7F CRC64;
MKHLLSGCLL LALAVGCPGP AAAKKKPKAK LGALLLGKDS LSKDEYGKIV KGGVKKQGLF
TVIFKAKDNK LYFEIPDSAF GRTYMLANRV ASTSNAKDYV AGQMVGNPMV VNFTKDERSV
YMNLVQAANL VAASDPIRAS FDRNFLNPIL KAFKIVATHG HSVVIDVSAF FGTNEACLSP
IKTDSPITKL LGGGNSLKGT YVADASGLNE VKAFERNIEI KSTLSYNLTG GLTATPYSVR
MHRSLFVLPD DPMPKRYQDN RVGYFSELQN LYSSDKDRVE QRSFIRRWRV EPRPEDRDRY
FRGELVEPQR KIVFYVDSAF PAKWRQTIKD GILVWNKAFE AAGFKHVIEA RDYPAADSLF
DPDDMRYNCF KYATTATPNA MGPSHSDPRT GEILCADVLW YHNIVSLLHN WRFVQTGAVD
ERVRRPVFDD ELMRQSIKYA ASHEVGHTLG LMHNMGASYA FPVDSLRSPS FTRRYGTTPS
IMDYARNNYV AQPGDPERGV SLLPPELGVY DVYAINWGYR LVPGAATPAE EKPELDRWIA
AKAGDPMYEF GAQQMLGTID PTDLTEDLGN DHVKAGDLGI SNLKIVMRHL LDWTMERGER
YDAVEDVYKE LTRQYSRYLG HVMPLVGGIE YKEVRQGDGQ PAARRFVSRA RQREAMHWLL
RQARSYDAWL TPADVLNKME IDLNVNDKIR TTVVSSLLNG ATLYRIREGG LADPRLNYPL
DTYLSNLTQA LFIAPRGGRL TAAEQQLQGA AIAQMMRASG LEKAEPKKAA AAAADVAAFW
RDATAPSTLC DYGHIASSFS RINLGSAALS QGELGAIMLG RLRAVLAKYR SYRNQAVGST
RDFYNYQVFV IERLLNHQ
//
