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Database: UniProt
Entry: F9DD47_9BACT
LinkDB: F9DD47_9BACT
Original site: F9DD47_9BACT 
ID   F9DD47_9BACT            Unreviewed;       845 AA.
AC   F9DD47;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   31-JUL-2019, entry version 40.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   Name=feoB {ECO:0000313|EMBL:EGQ12130.1};
GN   ORFNames=HMPREF9419_2009 {ECO:0000313|EMBL:EGQ12130.1};
OS   Prevotella nigrescens ATCC 33563.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=997352 {ECO:0000313|EMBL:EGQ12130.1, ECO:0000313|Proteomes:UP000004575};
RN   [1] {ECO:0000313|EMBL:EGQ12130.1, ECO:0000313|Proteomes:UP000004575}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33563 {ECO:0000313|EMBL:EGQ12130.1,
RC   ECO:0000313|Proteomes:UP000004575};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z.,
RA   Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA   Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L.,
RA   Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D.,
RA   Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R.,
RA   San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S.,
RA   Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K.,
RA   Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGQ12130.1}.
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DR   EMBL; AFPX01000058; EGQ12130.1; -; Genomic_DNA.
DR   RefSeq; WP_004367494.1; NZ_GL982465.1.
DR   STRING; 997352.HMPREF9419_2009; -.
DR   EnsemblBacteria; EGQ12130; EGQ12130; HMPREF9419_2009.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; GCF_000220235-HMP:HMPREF9419_RS09090-MONOMER; -.
DR   Proteomes; UP000004575; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   Gene3D; 2.30.30.90; -; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF04023; FeoA; 1.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SMART; SM00899; FeoA; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000004575};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004575};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    433    453       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    489    510       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    567    588       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    600    620       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    662    681       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    787    809       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    821    844       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN      139    301       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
FT   REGION       72    133       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     74    111       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   845 AA;  94284 MW;  76DD9D1E11C05562 CRC64;
     MKLSELKTGE AGIIVKVSGH GGFRKRIIEM GFISGKEVKV LLNAPLKDPV KYRIMGYEVS
     LRHNEADLIE VQPIGNSLQD TTDNDSQDTG TNNDNAGKKT QYPTDSTYNP PLEADPSDPY
     EPTLAPDEEE KRHNQQLHTI NVALVGNPNC GKTSLFNFAS GAHERVGNYS GVTVDAKYGY
     TDMMGYHFEL VDLPGTYSLS AYSPEELYVR KQLVDKTPDI VVNVIDASNL ERNLYLTTQL
     IDMNVPMVCA LNMYDEVENR GDHIDYKKLG MLLGVPMVPT VFTSGRGVRE LFQTIIQNCE
     GKKGDAPLYR HIHINHGHEI ENGIAEIQEH LNEESDASQK YSTRYLAIKL LENDKEAERL
     VKSFPDATEI MQHRDETARR VKEETGKDSE TAIMDAKYGF IHGALQEVHY TTGKGKDAYD
     TTRTIDKILT NKYLGFPLFF LILFVMFTAT FSLGQYPMDW IDAGVAWISE VLNNALPDGP
     VKAMLVDGAI AGVGAVIVFL PQILILYFFI SYMEDCGYMS RAAFIMDRLM HKMGLHGKSF
     IPLIMGFGCN VPAVMATRTI ESKRSRLVTM LVLPMMSCSA RLPIYIMITG SFFAARYRSA
     VMMLLYAIGI AMAVLLARLF SKTLVKGEDT PFVMELPPYR FPTWKAIGRH TWEKGKQYLK
     KMGGIILVAS IIVWALGYFP VPDNPNLGNQ ARQEQSYIGQ IGKTIEPVFR PMGFNWRLDV
     GLLAGVGAKE IVASTMGVLY TNNDSFGDDN TYSDDSHKYE ALRHQMTADV AKQNHISYAQ
     AEPLARLTAF CFLLFVLLYF PCVATIAAIK GETGSWKWGI FAAVYTTALA WIVSAVVYQV
     GVLLL
//
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