ID   F9G291_FUSOF            Unreviewed;       964 AA.
AC   F9G291;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Pep3/Vps18/deep orange beta-propeller domain-containing protein {ECO:0000259|Pfam:PF05131};
GN   ORFNames=FOXB_12773 {ECO:0000313|EMBL:EGU76752.1};
OS   Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU76752.1};
RN   [1] {ECO:0000313|EMBL:EGU76752.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fo5176 {ECO:0000313|EMBL:EGU76752.1};
RX   PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA   Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT   "A highly conserved effector in Fusarium oxysporum is required for full
RT   virulence on Arabidopsis.";
RL   Mol. Plant Microbe Interact. 25:180-190(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the VPS18 family.
CC       {ECO:0000256|ARBA:ARBA00010454}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGU76752.1}.
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DR   EMBL; AFQF01003186; EGU76752.1; -; Genomic_DNA.
DR   AlphaFoldDB; F9G291; -.
DR   STRING; 660025.F9G291; -.
DR   PaxDb; 5507-FOXG_09431P0; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16462; RING-H2_Pep3p-like; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR007810; Pep3_Vps18.
DR   InterPro; IPR011044; Quino_amine_DH_bsu.
DR   PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR23323:SF26; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG; 1.
DR   Pfam; PF05131; Pep3_Vps18; 1.
DR   SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   PROSITE; PS50236; CHCR; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          21..433
FT                   /note="Pep3/Vps18/deep orange beta-propeller"
FT                   /evidence="ECO:0000259|Pfam:PF05131"
FT   REGION          236..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          812..846
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        236..250
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   964 AA;  108886 MW;  4434EFF7814AF94F CRC64;
     MALDLQDGFV AANGVPDLEE PIFTIERVQL QFSVAADFVA AQVANNVIVL ALSNGRILRI
     DLERPEDIDD IDLPKKPSEI GMIRRMFLDP TASHLIVCTA LGENYYLHSQ SKHPRPLGRL
     RGVSIESVAW NPSLPTASTR EILIGASDGN IYEAFIETSK EFYKKEVKHL KNLHKLPDGP
     ITGLWVDNLQ NNKSDLRRVV IATQTRLFHL VGRIGFGHDG SGSVYTRLFE SEQPVVHELS
     RTTSGAPSSL AVSPDPPDSG PYDDDIPDRA YAWLSYQGVF HGKLLNQPVD SNLGTKVFSE
     SHMLSRAQIL SPENSERRVP TTEAIDAIAL TQWHIVHLVG GRVITTNRLT GKMVSEHDVI
     GQGQKPLGFS VDIQKNTFWL FTSDEIFEIV VRDEERNIWE IMTKLKEFEP ALQHARTPLQ
     KETVAAAYGD HLAKNGHWLE AATVYGRSNK PFEDIALSII DNNQPDALRK FLLTKLASLK
     KSAVMQRMMI AGWLIEVFMS KLNTLDDTIN TQAEPSEHLN STESRKLLES VRKEFRDFVD
     KYKNDLDRKM VYDVISSHGR EGELLYFANA VNDYNYVLSY WVQRERWNEV LNVLKKQTDP
     EVFYRYSSVL MTYVAPELVE ILMRHADLKP RNLIPAFLEY NRTFSGGPNA QNQAIRYLNY
     AVYQLNSKDA AVHNTLVSIY ASHSSKDESG LLSYLQAQGD EPRYDPDFAL RLCIQHHRTL
     SCVHIYTSMG QYLQAVDLAL SHGEVELAAV IADRPMSNPQ LRKRLWLAVA RKVISQSNGI
     KTAIEFLKRC DLLKIEDLIP FFPDFVVIDD FKEEICAALE DYSRNIDNLK KEMDESSQTA
     TNIKVDIAAL DHRYAIVEPG EKCYTCGLPL LSRQFFVFPC QHSFHSDCLG RKVLEQAGVG
     KSTRIRELQT QIQKGLVSGT QRETVVAELD ALVASACILC SDLAIKRIDE PFITHNDNVN
     EWAL
//