ID F9G314_FUSOF Unreviewed; 1096 AA.
AC F9G314;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=FOXB_13046 {ECO:0000313|EMBL:EGU76453.1};
OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU76453.1};
RN [1] {ECO:0000313|EMBL:EGU76453.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo5176 {ECO:0000313|EMBL:EGU76453.1};
RX PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT "A highly conserved effector in Fusarium oxysporum is required for full
RT virulence on Arabidopsis.";
RL Mol. Plant Microbe Interact. 25:180-190(2012).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU76453.1}.
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DR EMBL; AFQF01003279; EGU76453.1; -; Genomic_DNA.
DR AlphaFoldDB; F9G314; -.
DR STRING; 660025.F9G314; -.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03485; MutL_Trans_hPMS_1_like; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF41; MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763}.
FT DOMAIN 217..359
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 429..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..733
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1096 AA; 120167 MW; 279E58CB1AA69CE7 CRC64;
MSISVLPPSL AHLLRSSSSL PDPLSIIKEL VDNSIDAGAT SIEITVAPNT VDKVQVRDNG
CGIQVDDYKS LGRRSHTSKL RNFDELHLKG GKTLGFRGEA LASANYLATI KITTRTAQDP
IASLLLLNTK SGGISRQQPV SAPVGTTVQA LNLFQNLPVR KQNAIKVSRK TLADIRRLLE
RYAIALPHIR LSFKVPGSSI QPWVYTPCSA PSTREAITQV FGHALTTQLV AVSSDSRAGA
TSTEVQSKNL KIVASLPKPD SDANIIKGKG AFISVDSRPI SSSKSTGKKL VSIFRSSISA
VLNSPENSRA PSNAFMQLSI QCSPGSYDPN VTPSKDELLF VDEPAVLSCF QNLCDSVYTK
KFLGDKELQH KLVALEKSLS LLPWASKTVE PRRRDGARLD IMEKELLLTD QDLVGSLNDK
PERVLGGTGV FGSGERASPA AFTVPTSPKK SSRSGNLDET RGPKKAQPVQ EMMRTRLTVN
LSRRETASTD LDGKEGLIPV HVTPRRAATP PVRDELQSNS RRRGLTLNRR FGNIDDYFRS
SRDEPIQIAT DETATPEIPH TRSYLTSVSH NRRLPLKELS ESLLNLFREY EEEDYEDESD
DESSFNLPFA GPNAVPSPRT SPRREAPSFS SQPFRPLLGQ QSIRNSMPDL QLTLPANLQT
PPSSDPTVAH NSTRRDSRRQ STNNILARAQ RSSRGSVVPS VNRRSGDELR QSRLLLGSGP
TTSQGRRRSD QVCPGEFSSQ AYAQSWLSDQ VPHNHLSSCG GMRDSERSQP QGNKQWSHSL
QVLLQRTPPP QQATGSDEEA TGEYNPAPLD HIHDQHNEGF YSRSFKRQRR CSSVSTSESA
ELDSRRLLMK RQRIHANGGR LKRIASTKLP LEIISQNDST VNLSVKVEVQ MCELQAAALE
FTNSGRATKP DLALQFRNMD EVEVVDRRLR RVTESWLKGN PSVTGNWGKG GALACGDCLY
DGTTKLTRLE MLGCWAAGLD GQPAEVDPET PQEDVGYIDG WGAFEAKWRL MGTSKPDSRQ
QRGKESAAIE GQGLARAKVK MGTGIPTLTQ LPLVSALCST GRRFDVVMTN SSAQHRPIPH
SDIETSAAGK KRLCPT
//
