ID F9G7W0_FUSOF Unreviewed; 405 AA.
AC F9G7W0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=FOXB_14742 {ECO:0000313|EMBL:EGU74726.1};
OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU74726.1};
RN [1] {ECO:0000313|EMBL:EGU74726.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo5176 {ECO:0000313|EMBL:EGU74726.1};
RX PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT "A highly conserved effector in Fusarium oxysporum is required for full
RT virulence on Arabidopsis.";
RL Mol. Plant Microbe Interact. 25:180-190(2012).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU74726.1}.
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DR EMBL; AFQF01003644; EGU74726.1; -; Genomic_DNA.
DR AlphaFoldDB; F9G7W0; -.
DR STRING; 660025.F9G7W0; -.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 64..322
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 405 AA; 44633 MW; 0BF43466BF743CA3 CRC64;
MKMQSLICHG LRLLQVVQRP LACFHKALDG VFVLIKFSLI LLPSQQSAIS VKLGKEMESP
KRVLVTGGSG FLGGHVVRQL LKDAVTTVAI VSRHPKMPAD VADESHVSLQ AADLTVPSHI
EQVFETFKPH AVIHTASPSY LDTPANLMKA NIDGTKALLK AASACADTDV FVFTSSDSAV
IPTQEPLSEE NAVLYDETNA PNAYAMSKAA AERLVIASNS EVLRTAAIRI PATYGEYDTN
FVPQLVQSIR RKEHKMQVGN DTKVFEFLYV KKAAEAHILA MKALLDLETR DKAGGEAFFI
SDGKPQKFFD FSRKFYAAAG HPVALEEVTK IPFFVMQAMA STAEWVYWVL TLGYIKPGMR
RTAIDHLDSG CCWSLDKAKR ILGYEPVADQ DEAIRKTMEW AMKTL
//
