ID F9PIG0_9ACTO Unreviewed; 329 AA.
AC F9PIG0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Inositol 2-dehydrogenase {ECO:0000313|EMBL:EGV14558.1};
DE EC=1.1.1.18 {ECO:0000313|EMBL:EGV14558.1};
GN Name=idhA {ECO:0000313|EMBL:EGV14558.1};
GN ORFNames=HMPREF9058_1713 {ECO:0000313|EMBL:EGV14558.1};
OS Actinomyces sp. oral taxon 175 str. F0384.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=944560 {ECO:0000313|EMBL:EGV14558.1, ECO:0000313|Proteomes:UP000004281};
RN [1] {ECO:0000313|EMBL:EGV14558.1, ECO:0000313|Proteomes:UP000004281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0384 {ECO:0000313|EMBL:EGV14558.1,
RC ECO:0000313|Proteomes:UP000004281};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGV14558.1}.
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DR EMBL; AFUR01000001; EGV14558.1; -; Genomic_DNA.
DR RefSeq; WP_009747366.1; NZ_AFUR01000001.1.
DR AlphaFoldDB; F9PIG0; -.
DR eggNOG; COG0673; Bacteria.
DR Proteomes; UP000004281; Unassembled WGS sequence.
DR GO; GO:0050112; F:inositol 2-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR030827; Myo_inos_IolG.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR04380; myo_inos_iolG; 1.
DR PANTHER; PTHR42840:SF3; BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED; 1.
DR PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGV14558.1}.
FT DOMAIN 3..119
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 133..328
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 329 AA; 34849 MW; C27DD40FBF98B109 CRC64;
MLSIAVIGAG RIGHVHAKTI AAHPQAELAL VCDPFEDAAE KLAATYGARS CKDAEEVFAD
PEIDAVIVGS PTPLHIPHLL AAAKAGKAVL CEKPIALDMK DVEAAQAELD AVTVPVMFGF
NRRFDPSFAA ARAAVEAGKI GDIEQLTIIS RDPAAPPAEY IKVSGGIFRD MTIHDFDTAR
FFLGEIEEVY AAGQNLDPAL KDTGDFDAAV VTLKAASGAV ATIINNRHCS SGYDQRLEAS
GREGALFAEN IRATTVRLSN GEVTDAQEPY LDFFLERYAD AYRIELSAFI EAVEAGTTPP
TGIEDAIAAL RLAEAATESA HSGQPVRLS
//
