ID F9PMM0_9ACTO Unreviewed; 455 AA.
AC F9PMM0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Na+/H+ antiporter family protein {ECO:0000313|EMBL:EGV12342.1};
GN ORFNames=HMPREF9058_0749 {ECO:0000313|EMBL:EGV12342.1};
OS Actinomyces sp. oral taxon 175 str. F0384.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=944560 {ECO:0000313|EMBL:EGV12342.1, ECO:0000313|Proteomes:UP000004281};
RN [1] {ECO:0000313|EMBL:EGV12342.1, ECO:0000313|Proteomes:UP000004281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0384 {ECO:0000313|EMBL:EGV12342.1,
RC ECO:0000313|Proteomes:UP000004281};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGV12342.1}.
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DR EMBL; AFUR01000006; EGV12342.1; -; Genomic_DNA.
DR RefSeq; WP_009407292.1; NZ_AFUR01000006.1.
DR AlphaFoldDB; F9PMM0; -.
DR eggNOG; COG2056; Bacteria.
DR Proteomes; UP000004281; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..86
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 154..449
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 455 AA; 47504 MW; 7A5883C12ECC9F59 CRC64;
MNAIILAVLV MLILAMLRVH VVLSLFVGAL AGGLSAGLGV SRTMVAFQNG LADGAQIALS
YALLGAFAMA VAHSGLPQLL ANWLIGRIEN DDESASRKAV RTTTMLVLGG LTTMAIMSES
LIPVHIAFIP LVVPPLLIVM SRLQLDRRAV ACAITFGLVT TYMFLPLGFG RVFLYNTLYR
NIKEAGLDVS QVSATQAMGI PALGMVAGLL IAVFVTYRKP RVYQVDAGSG VGSGEEVSGP
VEVDRHKIRV ALVAVVACFA VQAFLTWTKS EADPLLVGAL TGLLLFMATR VVTIAEADDV
FTGGMRMMAL IGLIMITAQG FAKVLKETKQ IEPLVKSATS LFAGSKPAAA FVMLLVGLIV
TMGIGSSFST LPIISAIYVP LCVSLGFSPV ATVSLIGTAG ALGDAGSPAS DSTLGPTAGL
NADGQHDHMR DSVIPTFLHF NIPLLIAGWI AALVL
//
