ID F9UMB1_LACPL Unreviewed; 768 AA.
AC F9UMB1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:CCC78350.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:CCC78350.1};
GN OrderedLocusNames=lp_0910 {ECO:0000313|EMBL:CCC78350.1};
OS Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS (Lactobacillus plantarum).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=220668 {ECO:0000313|EMBL:CCC78350.1, ECO:0000313|Proteomes:UP000000432};
RN [1] {ECO:0000313|EMBL:CCC78350.1, ECO:0000313|Proteomes:UP000000432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1
RC {ECO:0000313|Proteomes:UP000000432};
RX PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W., Stiekema W.,
RA Lankhorst R.M., Bron P.A., Hoffer S.M., Groot M.N., Kerkhoven R.,
RA de Vries M., Ursing B., de Vos W.M., Siezen R.J.;
RT "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN [2] {ECO:0007829|PDB:3DMN}
RP X-RAY CRYSTALLOGRAPHY (1.66 ANGSTROMS) OF 597-767.
RA Tan K., Zhou M., Gu M., Joachimiak A.;
RT "The crystal structure of the C-terminal domain of a possilbe DNA helicase
RT from Lactobacillus plantarun WCFS1.";
RL Submitted (JUL-2008) to the PDB data bank.
RN [3] {ECO:0000313|EMBL:CCC78350.1, ECO:0000313|Proteomes:UP000000432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1
RC {ECO:0000313|Proteomes:UP000000432};
RX PubMed=22156394; DOI=10.1128/JB.06275-11;
RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA Kleerebezem M., van Hijum S.A.F.T.;
RT "Complete resequencing and reannotation of the Lactobacillus plantarum
RT WCFS1 genome.";
RL J. Bacteriol. 194:195-196(2012).
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DR EMBL; AL935263; CCC78350.1; -; Genomic_DNA.
DR RefSeq; WP_003641150.1; NC_004567.2.
DR RefSeq; YP_004888864.1; NC_004567.2.
DR PDB; 3DMN; X-ray; 1.66 A; A=597-767.
DR PDBsum; 3DMN; -.
DR AlphaFoldDB; F9UMB1; -.
DR SMR; F9UMB1; -.
DR STRING; 220668.lp_0910; -.
DR EnsemblBacteria; CCC78350; CCC78350; lp_0910.
DR KEGG; lpl:lp_0910; -.
DR PATRIC; fig|220668.9.peg.770; -.
DR eggNOG; COG3973; Bacteria.
DR HOGENOM; CLU_010312_4_1_9; -.
DR OrthoDB; 9787585at2; -.
DR PhylomeDB; F9UMB1; -.
DR Proteomes; UP000000432; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR048228; HelD_bacillota.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; NF041464; HelD_BACSU; 1.
DR PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3DMN};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000000432}.
FT DOMAIN 209..601
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 230..237
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 768 AA; 88001 MW; 45E04EE76FF9E436 CRC64;
MAKSIKAAEQ EHLDHVVAKI KVAEEQQSQT ITRSEKDQAD IKRDLLNNIN IKTDSYEGMM
ETGLSVRQQQ QMMDERQNSW KHATKQLSTL KKLEKNAYFA RIDFHETGEP KPETIYIGLS
SFSDTPDHFL IYDWRAPISS IYYDGGLGHV TYQTPDGEQT VNVKLKRQLM VENGQIVTVY
DTDEAVGDSM LLEVLDEKSD VKMKSIVTTI QKEQNTIIRD TSSDLLFVQG AAGSGKTSSV
LQRVAYLLYR YRGNLTAGQV ILFSPNQLFN DYINQVLPEL GEQNMVQMTY FQYASYRLPH
MQVETLQQRF ETENTPQMAK ITKLEGSLAF FNAVTTYGRH LEQADMRFRN ITLNDEVIIS
REKIKSIYYS FNENYHLANR LSATKEELIK ILNRKVESEM RSKWVEEAVQ DLSREEINQL
YGNQPREFKN GDKEFKFLAR KIVMQRLGKA RTQIVRNRFL SINMQYAHFL REVPKIIKLA
DHGISAADWD ATVERKLAEI KERHISLTTV SAYMYLHDLM TGKHGQRDIR FVFLDEIQDY
NAFQLAFLKF SFPQARFTML GDLNQAIFTK ENSHSLINEL ATLFDPEKTR VVQLTKSYRS
TQQITDFTKE ILVNGEAVTA FDRQGDLPNV VVTPNFEAGV DQVVDQLAMN DSERDTTAII
GKSLAECEAL TKALKARGEQ VTLIQTENQR LAPGVIVVPS FLAKGLEFDA VIVWNANQEN
YQREDERQLL YTICSRAMHE LTLVAVGSLS PLLARVNHAL YTLNEAKV
//
