ID F9UP85_LACPL Unreviewed; 748 AA.
AC F9UP85;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Maltose phosphorylase {ECO:0000313|EMBL:CCC79024.1};
DE EC=2.4.1.8 {ECO:0000313|EMBL:CCC79024.1};
GN Name=mapA {ECO:0000313|EMBL:CCC79024.1};
GN OrderedLocusNames=lp_1730 {ECO:0000313|EMBL:CCC79024.1};
OS Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS (Lactobacillus plantarum).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=220668 {ECO:0000313|EMBL:CCC79024.1, ECO:0000313|Proteomes:UP000000432};
RN [1] {ECO:0000313|EMBL:CCC79024.1, ECO:0000313|Proteomes:UP000000432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1
RC {ECO:0000313|Proteomes:UP000000432};
RX PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W., Stiekema W.,
RA Lankhorst R.M., Bron P.A., Hoffer S.M., Groot M.N., Kerkhoven R.,
RA de Vries M., Ursing B., de Vos W.M., Siezen R.J.;
RT "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WCFS1;
RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA Kleerebezem M., van Hijum S.A.F.T.;
RT "Complete resequencing and reannotation of the Lactobacillus plantarum
RT WCFS1 genome.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CCC79024.1, ECO:0000313|Proteomes:UP000000432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1
RC {ECO:0000313|Proteomes:UP000000432};
RX PubMed=22156394; DOI=10.1128/JB.06275-11;
RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA Kleerebezem M., van Hijum S.A.F.T.;
RT "Complete resequencing and reannotation of the Lactobacillus plantarum
RT WCFS1 genome.";
RL J. Bacteriol. 194:195-196(2012).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
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DR EMBL; AL935263; CCC79024.1; -; Genomic_DNA.
DR RefSeq; WP_003640464.1; NC_004567.2.
DR RefSeq; YP_004889538.1; NC_004567.2.
DR AlphaFoldDB; F9UP85; -.
DR STRING; 220668.lp_1730; -.
DR CAZy; GH65; Glycoside Hydrolase Family 65.
DR EnsemblBacteria; CCC79024; CCC79024; lp_1730.
DR GeneID; 77218124; -.
DR KEGG; lpl:lp_1730; -.
DR PATRIC; fig|220668.9.peg.1459; -.
DR eggNOG; COG1554; Bacteria.
DR HOGENOM; CLU_006285_2_2_9; -.
DR OrthoDB; 9758855at2; -.
DR PhylomeDB; F9UP85; -.
DR Proteomes; UP000000432; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0050082; F:maltose phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF14; MALTOSE PHOSPHORYLASE; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:CCC79024.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000432};
KW Transferase {ECO:0000313|EMBL:CCC79024.1}.
FT DOMAIN 14..261
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 318..674
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 684..745
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT ACT_SITE 482
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 353..354
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 587..588
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 748 AA; 85675 MW; D1F793496814D375 CRC64;
MKRIFDVNPW HVLTTDFKPE NKRLQESMTS LGNGYMGMRG FFEEDYTGDT LPGIYLGGVW
YPDKTRVGWW KNGYPEYFGK VINAVNFIKI NFKLNGTKID LATANFSDFK LDLDMQHGTL
TRSFIVDQDG QRVRVTFERF LSVAQKELSV QKVTFENLSD QAVELKVASA LDADVKNEDA
NYDEHFWNVH EVTDDRLIAQ TVPNDFGTPQ FTSGMQVSYV TSLTHKAAEV TDTATVDRYF
GTLEAGASVS FEKRVVVVTS RDYPTDDAIM TALQRLTDTV SAQSFDDLLA AHEAGWADRW
QQSDIQIEGD TEAQQGMRFN LFELFSTYYG DDPRLNIGPK GFTGEKYGGA TYWDTEAFAV
PVYLGITKPE VTRNLLMYRY KQLDGAYHNA RQQGLDGALF PMVTFNGIEC HNEWEITFEE
IHRNGDIAFA IYNYTRYTGD TSYVLHEGSK VLTEISRFWA DRVHFSKRNQ QYMIHGVTGP
DEYENNVDNN FNTNYLAQWT LKYTLEILDQ VSDDQAAALN VTAEERAHWQ DIVDRMYLPY
DKDLDIFVQH DGYLDKDLAP VSAIPADQLP INQHWSWDHI LRSPYIKQGD VLQVMYDFID
DFSKTQLKHN FDFYEPMTVH ESSLSPAIHA VLAADLHYED KAVAFYNRTA RLDLDNYNND
TVDGLHITSM TGGWIAMVQG FAGMRVHDGQ LSYRPFLPKQ WTKYSFRQVF RDRIIEVTVD
HDGTTLKLIA GEPIDVQVDG TTQTLTQN
//
