ID F9VG52_LACGL Unreviewed; 389 AA.
AC F9VG52;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Class I SAM-dependent rRNA methyltransferase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=LCGL_1843 {ECO:0000313|EMBL:BAK61303.1};
OS Lactococcus garvieae (strain Lg2) (Enterococcus seriolicida).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=420890 {ECO:0000313|EMBL:BAK61303.1, ECO:0000313|Proteomes:UP000008520};
RN [1] {ECO:0000313|EMBL:BAK61303.1, ECO:0000313|Proteomes:UP000008520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lg2 {ECO:0000313|EMBL:BAK61303.1,
RC ECO:0000313|Proteomes:UP000008520};
RX PubMed=21829716; DOI=10.1371/journal.pone.0023184;
RA Morita H., Toh H., Oshima K., Yoshizaki M., Kawanishi M., Nakaya K.,
RA Suzuki T., Miyauchi E., Ishii Y., Tanabe S., Murakami M., Hattori M.;
RT "Complete genome sequence and comparative analysis of the fish pathogen
RT Lactococcus garvieae.";
RL PLoS ONE 6:E23184-E23184(2011).
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DR EMBL; AP009333; BAK61303.1; -; Genomic_DNA.
DR RefSeq; WP_014025459.1; NC_017490.1.
DR AlphaFoldDB; F9VG52; -.
DR STRING; 420890.LCGL_1843; -.
DR KEGG; lgv:LCGL_1843; -.
DR PATRIC; fig|420890.5.peg.1817; -.
DR eggNOG; COG1092; Bacteria.
DR HOGENOM; CLU_014042_1_2_9; -.
DR Proteomes; UP000008520; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43042:SF3; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K; 1.
DR PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008520};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 4..64
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 174..347
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 389 AA; 43904 MW; FF93236D3191862D CRC64;
MKKITVKKQA ALKLRRAFPL IVAEDLKSTP QEDGFIDFVD EKENFLGRGY LSKQNKGAGW
LLSQIPEAIN QSFYEEKFEE AKRARLSFFQ DDLTTAFRIF NGEGDGLGGV TVDYYAEYAV
FSWYNPFIYT QSTDIIAAFQ SVYPEIKGIY EKIRFEGLSF ETRHIGGKIA PEPLAVMENG
VTYATYMNEG LMTGIFLDQK EVRGTLASGL AAGKTLLNMF SYTGAFSVAA AFGGASQTTS
VDLAKRSLDK TREQFTMNGF DPESQRIYVM DVFGYFNYAK KKELSYDVIV LDPPSFARNK
KKTFSVAKNY GELVQESIDI LNKEGLLIAS TNAANVSREK FRKMVEQALK NKNVKFEIFQ
EEHLPADFKV ASSFPEGDYL KVLFIQIKK
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