ID F9VKS2_ARTSS Unreviewed; 466 AA.
AC F9VKS2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN OrderedLocusNames=SFBM_0964 {ECO:0000313|EMBL:BAK56730.1};
OS Arthromitus sp. (strain SFB-mouse-Japan).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Candidatus Arthromitus.
OX NCBI_TaxID=1029718 {ECO:0000313|EMBL:BAK56730.1, ECO:0000313|Proteomes:UP000001636};
RN [1] {ECO:0000313|EMBL:BAK56730.1, ECO:0000313|Proteomes:UP000001636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SFB-mouse-Japan {ECO:0000313|Proteomes:UP000001636};
RX PubMed=21791478; DOI=10.1093/dnares/dsr022;
RA Kuwahara T., Ogura Y., Oshima K., Kurokawa K., Ooka T., Hirakawa H.,
RA Itoh T., Nakayama-Imaohji H., Ichimura M., Itoh K., Ishifune C.,
RA Maekawa Y., Yasutomo K., Hattori M., Hayashi T.;
RT "The lifestyle of the segmented filamentous bacterium: a non-culturable
RT gut-associated immunostimulating microbe inferred by whole-genome
RT sequencing.";
RL DNA Res. 18:291-303(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
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DR EMBL; AP012202; BAK56730.1; -; Genomic_DNA.
DR AlphaFoldDB; F9VKS2; -.
DR STRING; 1029718.SFBM_0964; -.
DR KEGG; asf:SFBM_0964; -.
DR eggNOG; COG1823; Bacteria.
DR HOGENOM; CLU_019375_0_3_9; -.
DR OrthoDB; 7778689at2; -.
DR Proteomes; UP000001636; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 466 AA; 50764 MW; 13E65345B516915E CRC64;
MENGFLKEFI MISSFNTLAW LIVLILLFTL MLFLKKKPIN FSNRMFIGTG LGIILGFAIQ
FAAKFPKNPL EITWINESTK WFSLFGNGFI DLIRMIVIPL IIISIIHIII SMKKDAKIKQ
LTIYTLVTLL STVAISAVVG FIISYVFKIG LNSTIASGSS NIKEVQSLID IFRNLIPKNP
IESMASSNVI AVVIFSIFIG TAAKKMGKIY AKTMETFNKL IEASHKIIVS ITMSIINLMP
YAIIPLLANT IAQRGIKSIL DVILFIVALY IAVIIMFLVH MILLSVFGFN PITYIKKAIP
VLILAFTSRS SLGCLPVTIE TLESMGCNSS TSTFVSSLGS TTGMNGCAGI FPAMLIIMIS
NITGYPINLG FMIMALLVVT ISSIGIAGVP GTATTSASIN LSAVGLGQYF DLTSPILAVD
PILDMARTML NINGVLTTSL IVDKNLKQID MNKFKDMNAK IDGSFM
//
