ID F9WAZ4_TRYCI Unreviewed; 218 AA.
AC F9WAZ4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=WGS project CAEQ00000000 data, annotated contig 2039 {ECO:0000313|EMBL:CCD14420.1};
DE Flags: Fragment;
GN ORFNames=TCIL3000_0_50360 {ECO:0000313|EMBL:CCD14420.1};
OS Trypanosoma congolense (strain IL3000).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCD14420.1, ECO:0000313|Proteomes:UP000000702};
RN [1] {ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|Proteomes:UP000000702};
RA Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J., Aslett M.,
RA Brown R., Corton N., Harris D., Hauser H., Gamble J., Gilderthorp R.,
RA McQuillan J., Quail M.A., Sanders M., Van Tonder A., Ginger M.L.,
RA Donelson J.E., Field M.C., Barry J.D., Berriman M., Hertz-Fowler C.;
RT "Divergent evolution of antigenic variation in African trypanosomes.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCD14420.1, ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|EMBL:CCD14420.1,
RC ECO:0000313|Proteomes:UP000000702};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCD14420.1}.
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DR EMBL; CAEQ01001507; CCD14420.1; -; Genomic_DNA.
DR AlphaFoldDB; F9WAZ4; -.
DR VEuPathDB; TriTrypDB:TcIL3000_0_50360; -.
DR OrthoDB; 128279at2759; -.
DR Proteomes; UP000000702; Unassembled WGS sequence.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF25; HISTONE DEACETYLASE 3; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000702}.
FT DOMAIN 77..218
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT NON_TER 218
FT /evidence="ECO:0000313|EMBL:CCD14420.1"
SQ SEQUENCE 218 AA; 23362 MW; 8351CD1AD8C0BB2F CRC64;
MACSSTEEDC FTRIPPVAIV FGDDVDASGT PPTVEHNRLV ADMVRHYACT PFTRREGSDD
ATGLAGDVFE WVDSSLPVVT LDDMAAYHDE SYVKYLSVRE TLSDVDVSVA TAGRSTLKDI
GDKSLGSYGS PSRPMSVLLP LNEDKKYNLV GESAPFAGLW KSTCAAVSGS LAAARLLAQP
GRFAAIHFFG GKRHAKYASA AGFCYINDVV IAALELRK
//
