ID F9WII1_TRYCI Unreviewed; 686 AA.
AC F9WII1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=WGS project CAEQ00000000 data, annotated contig 796 {ECO:0000313|EMBL:CCD17129.1};
GN ORFNames=TCIL3000_0_19760 {ECO:0000313|EMBL:CCD17129.1};
OS Trypanosoma congolense (strain IL3000).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCD17129.1, ECO:0000313|Proteomes:UP000000702};
RN [1] {ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|Proteomes:UP000000702};
RA Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J., Aslett M.,
RA Brown R., Corton N., Harris D., Hauser H., Gamble J., Gilderthorp R.,
RA McQuillan J., Quail M.A., Sanders M., Van Tonder A., Ginger M.L.,
RA Donelson J.E., Field M.C., Barry J.D., Berriman M., Hertz-Fowler C.;
RT "Divergent evolution of antigenic variation in African trypanosomes.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCD17129.1, ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|EMBL:CCD17129.1,
RC ECO:0000313|Proteomes:UP000000702};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCD17129.1}.
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DR EMBL; CAEQ01002599; CCD17129.1; -; Genomic_DNA.
DR AlphaFoldDB; F9WII1; -.
DR VEuPathDB; TriTrypDB:TcIL3000_0_19760; -.
DR OMA; QCSDHYE; -.
DR OrthoDB; 152156at2759; -.
DR Proteomes; UP000000702; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22696; E3 UBIQUITIN-PROTEIN LIGASE RNF26; 1.
DR PANTHER; PTHR22696:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF26; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000000702};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 633..675
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 290..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 74937 MW; 76F7DBB167D258E1 CRC64;
MSSGGWEGTP AEFTYAAEGD VDALRGWLLG YPDRINLQDA TTAETLLHRA AVCGRMSIVK
MLVSEFRADM GVPCGALLDT CLHIAAKRCD LVMLSFLIES GAPLKANALN RYPIDLVLEL
GVIDSDAAEC VKKLREYEEM LKLNGPSGAS TSVQSAGVPC PASLLSEVKK ESPKVYSAEG
FNSGTDASQI DLLFNMASAD ATVLEKPRPL RGSRNSGTER KSRTLHFFSS EERLPYDLHE
FREAYGAAFN FYESHEHYYA RGLLPYNYNG TVYYTPLILL VVKLHKSDKN GSRSESKGSP
IPSVMPGGNA NHVVNDSRGS HGSPYRSIID RKNLAGLLIN RKATYIDPCS GVIIPSEADV
GCRSLKQYVK DVVLACFEHI PPLTNNSAPA RAVCSSGPLF SFYPDMRYIK VHILRELSAT
YASVFTYDSS TRTVEGHIPI IKVIELPSLE VQVPGSTVGN VNEQPNTVSA LESDVVLRLP
LRLQFSMNGH FDDAPRVYFP TAASGTAMGQ VCYNMLHSIV IDCRTGAVNP DIFPSIQLWR
QHGSLQRVLL ELQEKATSLV MAYCKEDAVN LSGTYEFSAD WSTTGKGEGS STCGDDLLLL
SPPLLRTGGR SNFHEDSCAS VKGMSEAEVS SKCIFCLDRV KDALLLPCRH LALCTVCSAM
YGRNRGEGML CPICRAHVEQ TIKVYV
//
