ID F9WKI9_TRYVY Unreviewed; 320 AA.
AC F9WKI9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Oxidoreductase, putative {ECO:0000313|EMBL:CCD18009.1};
GN ORFNames=TvY486_0006470 {ECO:0000313|EMBL:CCD18009.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCD18009.1, ECO:0000313|Proteomes:UP000009027};
RN [1] {ECO:0000313|EMBL:CCD18009.1, ECO:0000313|Proteomes:UP000009027}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCD18009.1,
RC ECO:0000313|Proteomes:UP000009027};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|RuleBase:RU003682}.
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DR EMBL; CAEX01000203; CCD18009.1; -; Genomic_DNA.
DR AlphaFoldDB; F9WKI9; -.
DR VEuPathDB; TriTrypDB:TvY486_0006470; -.
DR OMA; FWHVGRE; -.
DR OrthoDB; 1380829at2759; -.
DR Proteomes; UP000009027; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47990:SF62; IRON_ASCORBATE OXIDOREDUCTASE DDB_G0283291-RELATED; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PRINTS; PR00682; IPNSYNTHASE.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000009027}.
FT DOMAIN 174..275
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 320 AA; 36792 MW; 4FFF9E8BB7679FBC CRC64;
MAGDSLPVID VGPLFQKEEG AVMSVARQID HACRTWGFFY VVGHPIPRER LDKLMEMAKT
FFSLPLEEKL KIDIKKSKHH RGYGCLNAEN VDPTKPYDCK ETFDMGFHLA EDHPDVVRGR
PLRGPNSHPT QVKGWVELMN QHYSDMQAFA LVILRAIALA IGLKEDFFDS KFEEPLSVLR
MVHYPPQKSQ SQYPLVCGEH TDYGIVTLLY QDAVGGLQVR NLANEWMDVE PIEGSFVVNI
GDMMNMWSNG RYRSTRHRVR ITTADRYSMP FFCEPNPYTV IECLENCHSP SDPPKYPPVR
AVDWLLKRFS ETYAYRQAKM
//
