ID F9WXM2_ZYMTI Unreviewed; 1303 AA.
AC F9WXM2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Putative RAD50 {ECO:0000313|EMBL:EGP90974.1};
GN ORFNames=MYCGRDRAFT_106885 {ECO:0000313|EMBL:EGP90974.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP90974.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP90974.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
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DR EMBL; CM001196; EGP90974.1; -; Genomic_DNA.
DR RefSeq; XP_003855998.1; XM_003855950.1.
DR STRING; 336722.F9WXM2; -.
DR EnsemblFungi; Mycgr3T106885; Mycgr3P106885; Mycgr3G106885.
DR GeneID; 13403225; -.
DR KEGG; ztr:MYCGRDRAFT_106885; -.
DR VEuPathDB; FungiDB:ZTRI_1.359; -.
DR eggNOG; KOG0962; Eukaryota.
DR HOGENOM; CLU_006184_0_0_1; -.
DR InParanoid; F9WXM2; -.
DR OMA; FSDYYYR; -.
DR OrthoDB; 5477220at2759; -.
DR Proteomes; UP000008062; Chromosome 1.
DR GO; GO:0030870; C:Mre11 complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR004584; Rad50_eukaryotes.
DR NCBIfam; TIGR00606; rad50; 1.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..232
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT REGION 928..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 213..240
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 300..348
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 395..440
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 472..529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 575..637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 693..774
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 846..925
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 973..1061
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1303 AA; 147884 MW; 50A8068D2324BAF7 CRC64;
MSKIEKLSIL GVRSFDHRKA MSIEFHAPLT LIVGMNGSGK TTIIECLKYA TTGIMPPGSK
GAAFIHDPAM AGEKEVMAQI KISFTSTENM KMVCTRNLQL TVTKTKPAGT FKTLDATIVM
RKAGERNVIS SRVAEIDTMM PRFLGVSRAV LESVIFCHQE ESLWPMSSPK DLKEKFDQIF
EALKYTKAID NIKILQKNKK IELVQLKANE EIAKANNDKA IKLQKKLQTL TDQSDAMRDQ
VKEYGVQQRE AQSRASEYFK KAGENELIVG KLQGRRIEKQ TKEESVRSLR ENIVEMTDSD
QQLETMLQQY DERVEAYQDD LSAKKGQYQA LEGNIQSARN RRIAKERECG SFEAQKESYD
RQVEGRKRMI KETARSHDIR GYDLEINDVQ AKAFMDRITK MAREQQEEFE QARLELQDLL
QQQQKELNRI NERKSALGQS KATARQTITG YERKISSIQS QRNQIDVDEG ARAALESRLQ
EKKGQLAKLQ EALASAAWDT KIDGDNSELR RLEDVREKLD AESADASRRG GETAQLDLLK
KGIQEDQRSL DTMTSSHGDK LTTVLGKAWS PTTIERDFER ALKAADAELE EAKKQRDGTN
SELGFLNSKL MERQAELANA KEDLKFAEKI VKEACGERPQ EYLAVMKRLE GERDVAKSAT
ENFGQIVEYL QSCIDEGERV NACKTCCRGF KNRAELSRMI EQVQRQQQQQ NGEDTKDELQ
DAEEALDLAK GANSQYEEWE RLSTKEIPTK KADLAKLEQE REKLVSQLEG LDTIFAEKSS
NKSSVTNVER TVRNIQKYVS GIAEKQSAVD GLESKLQSVG ASRGIEAVQT DVKKNSEDQK
SVRARIADAT RQQSKATANV NALQLEISNT QGSLSKADYE LREKKRLDAQ EEEYNKLTAD
QRDSIKKCDD ELQGLSAKLS TAQAKYDEIS SSGADKDREL QAKSSKMGAS LNKLKMAESE
IKAYHDRGGD EQLRQGKRAV EDLKAEEARH EAEKTEVIRN IKKAEELLHN HADTRRSISD
NQRYRRDLRQ LKKVVEEIAE LEEHNAEKDQ EENNRQAQRW SMRMNEISAK QSSVIGQLKS
LSDQIEADIE EYNVDYKDAA GSLKKAHVYV ETTKAAIEDL GRYGSALDKA IMKYHSLKME
EINRIIAELW QKTYQGTDID TILIRSEHET VKANKTYNYR VCMVKQDAEL DMRGRCSAGQ
KVLASIIIRM ALAECFGVNC GLIALDEPTT NLDSANIRAL ATSLSEIIKM RRQQSNFQLI
IITHDEEFLT QMGSSDYTDD YFRVFRDEHQ LSRIEKQSIS EVL
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